Results 231 to 240 of about 7,664,175 (345)

The Effectiveness of 2 Years of First Line Antiretroviral Therapy among HIV-Infected Children at an Integrated HIV-Care Clinic in Myanmar

, 2015

openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

The inTouch Integrated Care Framework - Reimagining Integrated Health Service Delivery. [PDF]

Int J Integr Care
Eljiz K, Medlin J, Harris-Roxas B, Ellis J, Derrett A, Loy G, Greenfield D.   +6 more
europepmc   +1 more source

Actionable policies for high-quality integrated long-term care: a LAUREL-project workshop [PDF]

Anam Ahmed, Iris W A Boot, Diane Whitehouse, Albert Alonso, Hubertus JM Vrijhoef   +4 more
openalex   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Cardio-rheumatology: integrated care and the opportunities for personalized medicine. [PDF]

Ther Adv Musculoskelet Dis
Ruiz Maya T, Ciosek A, Frech T, Maldonado G, Myers K, Chew E, Baba J, Donato A, Gupta D, Ross L.   +9 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Early Palliative Care in Patients with Glioblastoma: Co-Design of an Integrated Care Pathway. [PDF]

Healthcare (Basel)
van der Poort EKJ, Baas-Thijssen MCM, Oomes M, Vos MJ, Pieterman RM, Taphoorn MJB, de Vries I, Juffermans C, de Vries EF, van der Linden YM, Koekkoek JAF.   +10 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Federal Look-Alike Plan Termination Policy and Dual-Eligible Enrollment in Integrated Care Programs.

JAMA Health Forum
Ma Y, Roberts ET, Phelan J, Johnston KJ, Orav EJ, Meara ER, Figueroa JF.   +6 more
europepmc   +1 more source