Results 261 to 270 of about 7,664,175 (345)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Exploring integrated care for children with cerebral palsy: a stakeholder analysis. [PDF]

BMC Health Serv Res
Askeland S, Guise V, Aase K, Sogstad MKR.   +3 more
europepmc   +1 more source

A New Hospital-At-Home Model for Integrated Geriatric Care: Data from a Preliminary Italian Experience

Giulia Rivasi, Matteo Bulgaresi, Enrico Mossello, Salvatore Zimmitti, Riccardo Barucci, Irene Taverni, Sofia Espinoza Tofalos, Giacomo Cinelli, Giulia Nicolaio, Camilla Secciani, Arianna Bendoni, Giada Rinaldi, Djullye Miduri Da Silva Nakano, Chiara Barchielli, Lorenzo Baggiani, Guglielmo Bonaccorsi, Andrea Ungar, Enrico Benvenuti   +17 more
openalex   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Integrated care for people with multimorbidity into elective surgical pathways: mixed-methods co-design study. [PDF]

Br J Surg
Kamarajah SK, Dhesi J, Khunti K, Nirantharakumar K, Cockwell P, Hughes C, Stern P, Yeung J, Morton DG, Bhangu AA, Ahuja S.   +10 more
europepmc   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Patient-Reported Outcomes in Integrated Care: A Frontier of Opportunities and Challenges. [PDF]

Int J Integr Care
Anderson N, Hughes SE, Aiyegbusi OL, Collis P, Miller R, Calvert M.   +5 more
europepmc   +1 more source

Mobility Limitations and Self-Perceived Unmet Dental Needs Among Korean Adults: A Nationwide Multilevel Analysis for Integrated Care. [PDF]

Int Dent J
Kim HN, Kim NH.
europepmc   +1 more source

Mentoring the Next Generation of Integrated Care Stakeholders: Lessons Learned from the ERPIC Mentorship Program. [PDF]

Int J Integr Care
Wankah P, Derks M, Lindblom S.
europepmc   +1 more source