Results 71 to 80 of about 8,967,918 (378)

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Co-creating wellbeing and community connections: understanding what matters to older housing residents

International Journal of Integrated Care, 2019
Introduction: Hanover Scotland Housing Association is exploring ideas and opportunities to enhance the wellbeing, resilience and community connections of older people through a co-production and placed based approach that draws on their residents ...
Karen Barrie, Ben Hallet, Anne Hendry, Mandy Andrew, Helen Murdoch   +4 more
doaj   +1 more source

The implementation of integrated care: the empirical validation of the Development Model for Integrated Care [PDF]

BMC Health Services Research, 2011
Integrated care is considered as a strategy to improve the delivery, efficiency, client outcomes and satisfaction rates of health care. To integrate the care from multiple providers into a coherent client-focused service, a large number of activities and agreements have to be implemented like streamlining information flows and patient transfers.
Kees Ahaus, Robbert P. Vermeulen, Robbert Huijsman, Mirella Minkman   +3 more
openaire   +5 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Public Involvement in research within care homes: Benefits and challenges in the APPROACH Study [PDF]

, 2015
Public involvement in research (PIR) can improve research design and recruitment. Less is known about how PIR enhances the experience of participation and enriches the data collection process.
Davies, SL, Dickinson, A, Froggatt, K, Goodman, C, Martin, W, Masey, H, Morbey, H, Victor, C   +7 more
core   +3 more sources

Finnish care integrated?

International Journal of Integrated Care, 2002
The public Finnish social and health care system has been challenged by the economic crisis, administrative reforms and increased demands. Better integration as a solution includes many examples, which have been taken to use. The most important are the rewritten national and municipals strategies and quality recommendations, where the different sectors
openaire   +7 more sources

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

A critical realist evaluation of an integrated care project for vulnerable families in Sydney, Australia

BMC Health Services Research, 2020
Background Healthy Homes and Neighbourhoods (HHAN) Integrated Care Initiative was established to improve the care of families with complex health and social needs who reside in Sydney Local Health District.
E. Tennant, E. Miller, K. Costantino, D. De Souza, H. Coupland, P. Fotheringham, J. Eastwood   +6 more
doaj   +1 more source

Encouraging Integrated Care for Dual Eligibles [PDF]

, 2009
Outlines examples and elements of integrated care models for those eligible for both Medicare and Medicaid, including multidisciplinary care teams, comprehensive provider networks, and data sharing, that would eliminate inefficiencies and reduce ...
Lindsay Palmer, Melanie Bella
core