Results 171 to 180 of about 554,536 (332)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Intersectoral pathways of vulnerable patient groups in Southern Denmark

open access: yesInternational Journal of Integrated Care, 2015
Stine Lundstroem Kamionka   +4 more
doaj   +3 more sources

Supplementary file 7_Improving the management of acute asthma in children through an integrated care pathway: an implementation study protocol.docx

open access: green
Marta Montejo (16975220)   +12 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

ESVM integrated care pathways – a call for action [PDF]

open access: yesVasa, 2019
Vison A.   +22 more
openaire   +4 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Implementation of an integrated care pathway for severe aortic stenosis: a prospective cohort study of clinical profiles, safety, and outcomes. [PDF]

open access: yesFront Cardiovasc Med
González-Salvado V   +9 more
europepmc   +1 more source

The Exponential Phase of the Covid-19 Pandemic in Central Italy: An Integrated Care Pathway. [PDF]

open access: yesInt J Environ Res Public Health, 2020
Capalbo C   +16 more
europepmc   +1 more source

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