Results 21 to 30 of about 1,266 (208)

An integrative approach to improving patient care pathways [PDF]

International Journal of Health Care Quality Assurance, 2018
Purpose Globally, healthcare managers continue to struggle with increasing demands for their services being delivered with limited or shrinking resources. It is, therefore, clear that systems, processes and practices need to change to meet these challenges.
Radnor, Zoe, Williams, Sharon J.
openaire   +4 more sources

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

Feeding, Fear, and Acceptance: Caregivers’ Experiences of Nutritional Support During Childhood Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques, Mariana dos Santos Murra, Welinton Hirai, Ana Laura Balduino do Nascimento, Karla Emilia de Sá Rodrigues, Wilson Elias de Oliveira Junior   +5 more
wiley   +1 more source

A holistic approach is needed for women with an inflammatory arthritis in the different phases around pregnancy; the results of the CAPRI study

Frontiers in Global Women's Health
IntroductionWomen with inflammatory arthritis (IA) face significant challenges throughout preconception, pregnancy, and postpartum phases, including concerns about disease management and medication safety.
A. J. van Steensel – Boon, H. M. Wintjes, E. Röder, H. T. W. Smeele, L. J. C. Kranenburg - van Koppen, R. J. E. M. Dolhain, L. F. Perez-Garcia   +6 more
doaj   +1 more source

An integrated framework for verifying multiple care pathways [PDF]

2017 International Symposium on Theoretical Aspects of Software Engineering (TASE), 2017
Common chronic conditions are routinely treated following standardised procedures known as clinical pathways. For patients suffering from two or more chronic conditions, referred to as multimorbidities, several pathways have to be applied simultaneously.
Juliana Bowles, Marco B. Caminati, Suhyun Cha   +2 more
openaire   +3 more sources

Representation of Sickle Cell Disease Patients in Pediatric and Adult Care: What We Discovered Using Informatics for Integrating Biology and the Bedside (i2b2) Data

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Transitioning from pediatric to adult care is a high‐risk period for individuals with sickle cell disease (SCD). An initial observation at one academic medical center suggested a sex‐based disparity in clinic populations, prompting a national investigation.
Laurie J. Duckworth, Kholod Alhassan, Ada De La Osa, John Stephen, Yue Yao, Diana J. Wilkie   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Designing and incorporating integrated oral health care pathways for pediatric and adult patients: touchpoints in a dental setting

BMC Oral Health
Background Maintenance of oral health, prevention, and health promotion stand as primary competencies for dental graduates. Consequently, it is necessary to promote such an approach in dental schools, which are traditionally focused on treatment, to ...
Talieh Mahmoud Hashemi, Mahdia Gholami, Mohammad Reza Khami, Simin Z. Mohebbi, Armin Shirvani   +4 more
doaj   +1 more source

Building an integrated multidisciplinary care system for emergency surgery in abdominal cancer: a patient-centered perspective

Frontiers in Surgery
Abdominal oncologic emergencies demand urgent surgical decisions that may conflict with ongoing cancer therapies and patient preferences. Conventional fragmented care models often lead to delays, inconsistent decisions, and poor care transitions.
Qing Li, Jin-qiang Zhang
doaj   +1 more source