Results 41 to 50 of about 79,011 (263)

Dual-loop neural prediction-based trajectory tracking control for robotic arms [PDF]

PeerJ Computer Science
With the rapid growth of intelligent manufacturing, robotic arm trajectory tracking control faces challenges of high precision and fast response. Existing control methods suffer from lagging parameter convergence, loss of prediction accuracy at single ...
Tengfei Zhuang, Yuan Zhuang
doaj   +2 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Doped Highly Crystalline Organic Films: Toward High‐Performance Organic Electronics

Advanced Science, 2021
Today's organic electronic devices, such as the highly successful OLED displays, are based on disordered films, with carrier mobilities orders of magnitude below those of inorganic semiconductors like silicon or GaAs.
Michael F. Sawatzki, Hans Kleemann, Bahman K. Boroujeni, Shu‐Jen Wang, Joern Vahland, Frank Ellinger, Karl Leo   +6 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Broadband directional filter in multilayer liquid crystal polymer films at W-band

Frontiers in Photonics
In this work, a four-port directional filter (DF) with a broad passband and low reflection is proposed at the W-band, which comprises three unit filters at 92, 95, and 97 GHz, cascaded in series.
Mengfa Wang, Yiming Wang, Jun Qian, Zhaolin Li, Wenhui Xue, Victor Qi, Xijian Zhang, Haotian Ling, Gongbin Tang, Qingpu Wang, Aimin Song, Aimin Song, Chao Cao, Yifei Zhang   +13 more
doaj   +1 more source

Synthesis of High-Input Impedance Electronically Tunable Voltage-Mode Second-Order Low-Pass, Band-Pass, and High-Pass Filters Based on LT1228 Integrated Circuits

Sensors, 2022
This paper introduces two new high-input impedance electronically tunable voltage-mode (VM) multifunction second-order architectures with band-pass (BP), low-pass (LP), and high-pass (HP) filters.
Hua-Pin Chen, Shih-Jun Chen, Chih-Yang Chang   +2 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Statistical Timing Analysis for Subthreshold Circuit Based on Bayesian Inference

IEEE Access
Accurately predicting the delay distribution of subthreshold circuits is crucial for verifying the timing closure of digital circuits and estimating parameter yields.
Donglin Liu, Yuping Wu, Zhiqiang Li, Xuelian Zhang, Xi Tian   +4 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source