Results 181 to 190 of about 8,208,096 (281)

Protocol for isolation and cryopreservation of human peripheral blood mononuclear cells for high-resolution respirometry. [PDF]

STAR Protoc
Romero A, Timón-Gómez A, Willis JR, Perfler A, Lindlbauer T, Knoflach M, Gnaiger E.   +6 more
europepmc   +1 more source

The Same Integer Comes Back from Three Different Counts ── Integrate the Curvature, Count the Zeros of a Vector Field, Count the Passes of a Function ── A Height Function on a Torus Needs Four Critical Points and Cannot Have Three ── [Paper 316]

Paper 67 read m=4pi=2pichi(S^2) as Poincare--Hopf. This paper asks how many roads lead to chi──the answer is three, and none of them follows from the other two. No new mathematical theorem and no new law is claimed. Scope of this paper (scope note): No new mathematical theorem and no new law is claimed──the Gauss--Bonnet theorem, the Poincare--Hopf ...
openaire   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

MRI-Derived Evaluation of Liver Function and Its Extension to K-Edge Photon-Counting CT: Focus on Gadolinium-Based Functional Biliary Imaging. [PDF]

Diagnostics (Basel)
Asmundo L, Vicentin I, Ghilardi G, Monti CB, Vanzulli A, Rizzetto F, Mariani L, Steffani S, Centonze L, Mazzarelli C, Albano D, Sandro SD, Vanzulli A.   +12 more
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

An integrated monolithic photonic accelerometer with on-chip fringe-counting. [PDF]

Microsyst Nanoeng
Meng Y, Hu Q, Vatankhah E, Liu Z, Wang W, Hall NA.   +5 more
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

A model predictive control framework with fatigue life assessment for flywheel energy storage systems supported by active magnetic bearings. [PDF]

Sci Rep
Hashim A, Shaltout ML, El-Kashif E, Hussein BA.   +3 more
europepmc   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Deep learning survival analysis with time-varying covariates: extending PyCox to assess COVID-19 antiviral treatments and long-COVID associations. [PDF]

JAMIA Open
Baik SH, Xian H, Baye F, Fung KW, McDonald CJ.   +4 more
europepmc   +1 more source