Results 91 to 100 of about 277,131 (251)

Challenges with the implementation of an Integrated Disease Surveillance and Response (IDSR) system: systematic review of the lessons learned [PDF]

Health Policy and Planning, 2013
Despite a realistic strategy and availability of resources, multiple challenges still overwhelm countries grappling with the challenges of communicable disease surveillance. The Integrated Disease Surveillance and Response (IDSR) strategy is by far the most pragmatic strategy in resource-poor settings.
Revati K, Phalkey, Shelby, Yamamoto, Pradip, Awate, Michael, Marx   +3 more
openaire   +2 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Assessing the Resilience and Core Functions of Cameroon’s Integrated Disease Surveillance and Response (IDSR) System: A Nationwide Cross-Sectional Evaluation in 2023

Health Research in Africa
Introduction. Despite adopting IDSR in the early 2000s, Cameroon had yet to conduct a comprehensive nationwide evaluation of its surveillance system's effectiveness and operational gaps against global infectious threats. Methodology. This 2023 nationwide
Chanceline Bilounga Ndongo, Nestor Atangana Onana, Linda Esso, Protais Cyriaque Etene, Armelle Viviane Ngomba, Elise Ikoula Amougou, Annick Mfoulou Assala, Boris Kompguep, Manuella Efemba, Luc Bakebeg, Raoul Nembot, Durand YK Gameni, Loïc Tchoupo, Georges Alain Etoundi, Georges Alain Etoundi, André Arsène Bita Fouda, Jules Leon Owona Manga, Georges Nguefack-Tsague   +17 more
doaj   +1 more source

Community-owned resource persons for malaria vector control: enabling factors and challenges in an operational programme in Dar es Salaam, United Republic of Tanzania. [PDF]

, 2011
UNLABELLED\ud \ud ABSTRACT:\ud \ud BACKGROUND\ud \ud Community participation in vector control and health services in general is of great interest to public health practitioners in developing countries, but remains complex and poorly understood.
Chaki, Prosper P, Dongus, Stefan, Fillinger, Ulrike, Kelly, Ann, Killeen, Gerry F   +4 more
core   +6 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Health Problems Heat Up: Climate Change and the Public's Health [PDF]

, 2009
Examines the health effects of climate change, the needed public health response, concerns for communities at high risk, and state planning and funding for climate change assessments and strategies.

core  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Ready or Not? Protecting the Public's Health From Diseases, Disasters, and Bioterrorism, 2011 [PDF]

, 2011
Highlights examples of preparedness programs and capacities at risk of federal budget cuts or elimination, examines state and local public health budget cuts, reviews ten years of progress and shortfalls, and outlines policy issues and ...

core  

‘Next-Generation’ surveillance: an epidemiologists’ perspective on the use of molecular information in food safety and animal health decision-making [PDF]

, 2015
Advances in the availability and affordability of molecular and genomic data are transforming human health care. Surveillance aimed at supporting and improving food safety and animal health is likely to undergo a similar transformation.
Dufour, S., Muellner, P., Stärk, K.D.C., Zadoks, R.N.   +3 more
core   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source