Results 121 to 130 of about 277,131 (251)

Biomimetic Nanovaccine Integrating Dendritic Cell Exosomes with Tumor Cell Membranes for Sustained Prophylaxis Against Glioblastoma

Advanced Functional Materials, EarlyView.
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li, Dongya Zhang, Shiyu Wang, Changhe Pang, Meng Zheng, Bingyang Shi, Yan Zou   +6 more
wiley   +1 more source

Disease Surveillance Networks Initiative Asia: Final Evaluation [PDF]

, 2010
The DSN Initiative was launched in 2007 under the new strategy of the Rockefeller Foundation. The initiative intends:[1] To improve human resources for disease surveillance in developing countries, thus bolstering national capacity to monitor, report ...
Caridad A. Ancheta, Elaine S. Perez, Kerry Richter, Ma. Sandra B. Tempongko, Malee Sunpuwan, Ophelia M. Mendoza, Oranut Pachuen, Pratap Singhasivanon   +7 more
core  

Climate Variability and Ross River Virus Transmission in Townsville Region, Australia 1985 to 1996 [PDF]

, 2004
Background How climate variability affects the transmission of infectious diseases at a regional level remains unclear. In this paper, we assessed the impact of climate variation on the Ross River virus (RRv) transmission in the Townsville region ...
A. J. McMichael, Aaskov JG, Allard R, Australian Bureau of Statistics, Bowie C, Catalano R, Chatfield C, Checkley W, Curran M, Curriero FC, Doherty RL, Helfenstein U, Helfenstein U, Helfenstein U, Hennessy KJ, Kay BH, Liehne PF, Lindsay M, Lindsay MD, Lindsay MD, Mackenzie JS, McManus TJ, McMichael AJ, Nimmol JR, Russell RC, Shilu Tong, Shope RE, Tabachnick BG, Tong SL, Weinstein P, Wenbiao Hu, Whetton P   +31 more
core   +2 more sources

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Fluid Forces Control Structural Remodeling of Blind‐Ended Lymphatic Microvessels

Advanced Healthcare Materials, EarlyView.
Using innovative microfluidic biofabrication with fluid mechanical insights, we recapitulated the blind‐ended microanatomy and physiological drainage properties of capillary lymphatics. Our results reveal the interrelationship between intra‐ and extraluminal regions of lymphatic vessels due to flow‐induced sprouting and morphological changes that ...
Jacob C. Holter, Shashwat S. Agarwal, Joseph W. Tinapple, Joseph M. Barlage, Travis H. Jones, Jonathan W. Song   +5 more
wiley   +1 more source

Deep learning for infectious disease surveillance integrating internet of things for rapid response

International Journal of Electrical and Computer Engineering (IJECE)
Particularly in the case of emerging infectious diseases and worldwide pandemics, infectious disease monitoring is essential for quick identification and efficient response to epidemics. Improving surveillance systems for quick reaction might be possible with the help of new deep learning and internet of things (IoT) technologies. This paper introduces
Sumithra, Subramanian, Radhika, Moorthy, Venkatesh, Gandavadi, Lakshmi, Babu Seetha, Jancee, Balraj Victoria, Mohankumar, Nagarajan, Murugan, Subbiah   +6 more
openaire   +2 more sources

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Is prevention better than cure? An empirical investigation for the case of avian influenza [PDF]

, 2008
The new EU Animal Health Strategy suggests a shift in emphasis away from control towards prevention and surveillance activities for the management of threats to animal health. The optimal combination of these actions will differ among diseases and depend
Huirne, R., Jongeneel, R., Longworth, N.J., Saatkamp, H.W.   +3 more
core   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Disease Surveillance and the Academic, Clinical, and Public Health Communities

Emerging Infectious Diseases, 2003
The Emerging Infections Programs (EIPs), a population-based network involving 10 state health departments and the Centers for Disease Control and Prevention, complement and support local, regional, and national surveillance and research efforts.
Robert W. Pinner, Catherine A. Rebmann, Anne Schuchat, James M. Hughes   +3 more
doaj   +1 more source