Results 191 to 200 of about 277,131 (251)

Spatial and temporal epidemiological analysis in the Big Data era [PDF]

, 2015
Alvarado-Serrano, Anderson, Andrienko, Anon, Anon, Anon, Anon, Baker, Bell, Breiman, Brownstein, Brownstein, Brownstein, Brunker, Butler, Butler, Carneiro, Carrel, Carroll, Chan, Chew, Chunara, Clements, Collier, Collins, Correa, Costa, Cowen, de Glanville, Dhar, Dirk U. Pfeiffer, Dodge, Eastman, Elith, Elith, Eysenbach, Faghmous, Faria, Feizizadeh, Fernández, Firestone, Firestone, França, Freifeld, Gandomi, Gartner, Gibney, Giebultowicz, Gilbert, Ginsberg, Goodchild, Goodchild, Grein, Haklay, Hartley, Hay, Hay, Heipke, Heymann, Hirzel, Hirzel, Hongoh, Istepanian, Jankowski, Jones, Kambatla, Kamel Boulos, Kamel Boulos, Keller, Kim B. Stevens, Kuhn, Lawson, Lazer, Lee, Leetaru, Li, Liang, Ligmann-Zielinska, Malczewski, Malczewski, Martin, Mayer-Schönberger, Milinovich, Milinovich, Mortari, Mullins, Murray, Mykhalovskiy, Okabe, Oliver, Olsen, O’Driscoll, Peters, Pfeiffer, Pfeiffer, Pigliucci, Pigott, Porter, Prates, Pybus, Rutten, Sanchez-Matamoros, Sarojinie Fernando, Schadt, Scholkopf, Schutt, See, Signorini, Solanas, Sorensen, St Louis, Stevens, Stevens, Tatem, Tatem, Tolentino, Tran, van Zyl, van Zyl, Vatsavai, Wesolowski, Wesolowski, Wilson, Wilson, Wilson, Wing, Yemshanov, You, Zeldenrust, Ziegler   +129 more
core   +2 more sources

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

Advanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li, Zhongshao Chen, Qianqian Gao, Yuehan Gao, Ning Yang   +4 more
wiley   +1 more source

Early Detection and Inhibition of Post‐Surgical Cancer Recurrence by Synthetic Extracellular Vesicles

Advanced Science, EarlyView.
An implantable hydrogel is designed to hold gene transfection agents engineered to turn early recurrent tumor cells into generators of synthetic EVs. These synthetic EVs can express engineered miR‐26a (E‐miR‐26a) for highly sensitive detection and PD‐1 (a PD‐L1‐blocking agent) for therapeutic intervention, thereby enabling early detection and ...
Junli Zhang, Wenjia Chang, Ruolin Hu, Peiyan Su, Qin Zhou, Yanan Li, Zhenzhong Zhang, Kaixiang Zhang   +7 more
wiley   +1 more source

Mission de prospection pour l'élaboration de projets de recherche sur les arboviroses zoonotiques en Asie du Sud-Est. Rapport de mission du 22 août au 4 septembre 2010 [PDF]

, 2010
Chevalier, Véronique
core  

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

Advanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu, Wanpeng Zou, Yuekai Li, Jiayi Wang, Mingxuan Cai, Hongmin Cai   +5 more
wiley   +1 more source

Species Dependent Toxicity Comparison Outcome

Advanced Science, EarlyView.
By quantitatively assessing and comparing toxicity responses across different animal species and material compositions, our data reveal that toxicity rankings among different materials may be reversed across species. ABSTRACT Toxicity comparison plays a crucial role in material selection across diverse application fields.
Lian Xiao, Zhan Yu, Sihang Liu, Yuheng Liu, Chong Deng, Yugang Zhao, Yi Huang, Zhi‐Gang Zheng   +7 more
wiley   +1 more source

The score of integrated disease surveillance and response adequacy (SIA): a pragmatic score for comparing weekly reported diseases based on a systematic review. [PDF]

BMC Public Health, 2019
Mandja BM, Bompangue D, Handschumacher P, Gonzalez JP, Salem G, Muyembe JJ, Mauny F.   +6 more
europepmc   +1 more source

Implementing integrated disease surveillance and response.

Releve epidemiologique hebdomadaire, 2003
openaire   +1 more source

Integrating Radiomics and Computational Pathology to Predict Early Recurrence of Pancreatic Ductal Adenocarcinoma and Uncover Its Biological Basis in Tumor Microenvironment

Advanced Science, EarlyView.
Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.
Sihang Cheng, Fuze Cong, Shenbo Zhang, Rui Lv, Wenjia Zhang, Xinyi Ke, Juncheng Wu, Zhonghe Zhao, Kui Zhao, Di Dong, Ruofan Zhang, Zhengyu Jin, Max Seidensticker, Zhiwei Wang, Huanwen Wu, Xianlin Han, Nan Hong, Huadan Xue   +17 more
wiley   +1 more source

Laparoscopic Delivery of a MnO2‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin, Haoqi Pan, Ke Wu, Junjie Nan, Jinyao Dai, Yushun Chang, Hao Shen, Qingxuan Ye, Haowen Lu, Yuxuan Shen, Boqiang Liu, Ming Wu, Jicheng Yu, Xiujun Cai, Dong Cen   +14 more
wiley   +1 more source