Results 61 to 70 of about 241,458 (298)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Abstracts From the 2025 Health Care Systems Research Network (HCSRN) Annual Conference, St. Louis, Missouri

The Health Care Systems Research Network (HCSRN) comprises 19 learning health systems with integrated care delivery and embedded research units. The network’s annual conference serves as a forum for research teams from member institutions to disseminate ...
Research Network, Health Care Systems
core   +1 more source

Health satisfaction outcome from integrated autonomous mobile clinics

Scientific Reports
Autonomous mobile clinics (AMCs) have the potential to revolutionize healthcare delivery by bringing healthcare services to patients at the order of patient’s fingertips. Particularly, AMCs can act as an essential touch point of integrated care, which is
Yuzhang Huang, Shaoshan Liu, Zhongying Pan, Carl Wu, Herng-Chia Chiu, Xue Liu, Leiyu Shi   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Developing a model of mental health self-care support for children and young people through an integrated evaluation of available types of provision involving systematic review, meta-analysis and case study

, 2014
Background The mental health of children and young people (CYP) is a major UK public health concern. Recent policy reviews have identified that service provision for CYP with mental health needs is not as effective, responsive, accessible or child ...
Kirk, S., Peter Bower, Elvey, Rebecca, Bower, P., Catchpole, R, Susan Kirk, Steven Pryjmachuk, Bower, P, Pryjmachuk, S., Sarah Kendal, Elvey, R., Catchpole, R., Pryjmachuk, S; id_orcid, Rebecca Elvey, Kendal, S, Kendal, Sarah, Roger Catchpole, Kirk, Susan   +17 more
core   +1 more source

Process evaluation of a National Primary Eye Care Programme in Rwanda

BMC Health Services Research, 2018
Background Visual impairment is a global public health problem, with an estimated 285 million affected globally, of which 43% are due to refractive error.
Jennifer L. Y. Yip, Tess Bright, Sebastian Ford, Wanjiku Mathenge, Hannah Faal, on behalf of the Rwanda Primary Eye Care Process evaluation group   +5 more
doaj   +1 more source

Achieving Quality Integrated Care for Adolescent Depression: A Scoping Review

Journal of Primary Care & Community Health, 2022
Introduction: While primary care is often the first point of contact for adolescents with depression, more than half of depressed adolescents are either untreated or undertreated.
Diana Sarakbi, Dianne Groll, Joan Tranmer, Kim Sears   +3 more
doaj   +1 more source

A tool for improving the delivery of integrated intensive health care performance

International Journal of Integrated Care, 2019
L'International Journal of Integrated Care (IJIC) est une revue scientifique en ligne, en libre accès et évaluée par des pairs qui publie des articles originaux dans le domaine des soins intégrés sur une base continue. L'IJIC a un facteur d'impact de 5,120 (JCR 2020, reçu en juin 2021)
Javier Balladini, Pablo Bruno, Rafael Ignacio Zurita, Cristina Orlandi, Remo Suppi, Dolores Rexachs, Emilio Luque   +6 more
openaire   +5 more sources

INTEGRATING SOCIAL DETERMINANTS OF HEALTH IN CLINICAL CARE DELIVERY

Journal of the American College of Cardiology, 2020
Social needs such as transportation and housing, so called social determinants of health (SDOH) are important factors that modulate the effectiveness of medical therapy in chronic medical conditions such as heart failure.
Anekwe E. Onwuanyi, Diane Wirth, Faith Works-Fleming, Andrea Cafarelli, Michael Knauss, Modele Ogunniyi, Brandi Quinn, Jeff Herald, Amy Bick, Eva Gourrier, Tara Shropshire   +10 more
openaire   +1 more source