Results 101 to 110 of about 10,059,863 (274)

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Patient and Public Engagement in Integrated Knowledge Translation Research: Are we there yet?

Research Involvement and Engagement, 2019
Plain English summary There have been many attempts to improve how healthcare services are developed and delivered. Despite this, we know that there are many gaps and differences in practice and that these can lead to poor patient outcomes.
Davina Banner, Marc Bains, Sandra Carroll, Damanpreet K Kandola, Danielle E Rolfe, Caroline Wong, Ian D. Graham   +6 more
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Knowledge translation and integration of research evidence into practice: A national mandate

South African Family Practice
New medical knowledge is being rapidly added to the existing body of scientific understanding. However, the degree to which knowledge translation and the integration of research evidence into clinical practice are aligned and implemented remains unclear.
John Musonda, Deidre Pretorius, Christiaan Visser, Olufemi Omole   +3 more
openaire   +3 more sources

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

WordNet gloss translation for under-resourced languages using multilingual neural machine translation

, 2019
In this paper, we translate the glosses in the English WordNet based on the expand approach for improving and generating wordnets with the help of multilingual neural machine translation. Neural Machine Translation (NMT) has recently been applied to many
McCrae, John P., Chakravarthi, Bharathi Raja, Arcan, Mihael   +2 more
core   +1 more source

Balancing exploration and exploitation in transferring research into practice : a comparison of five knowledge translation entity archetypes [PDF]

, 2013
Background: Translating knowledge from research into clinical practice has emerged as a practice of increasing importance. This has led to the creation of new organizational entities designed to bridge knowledge between research and practice.
Girts Racko, Oborn, Eivor, Karl Prince, Eivor Oborn, Prince, Karl, Racko, Girts, Michael Barrett, Barrett, Michael   +7 more
core   +2 more sources

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

Supporting partnerships in knowledge mobilization: what existing implementation strategies can tell us

Research Involvement and Engagement
Background The need for partnership between knowledge producers and knowledge users to foster effective implementation is well-established in the implementation science literature.
Nicole E. MacKenzie, Christine T. Chambers, Kathryn A. Birnie, Isabel Jordan, Christine E. Cassidy   +4 more
doaj   +1 more source