A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu +4 more
wiley +1 more source
Trainee-led research using an integrated knowledge translation or other research partnership approaches: a scoping reviews. [PDF]
Cassidy CE +13 more
europepmc +1 more source
Object-oriented modeling of meta-information for semantic schema enrichment and (semi)automated schema transformation [PDF]
Keim, Daniel A. +2 more
core
To solve complex problems, it makes sense to seek diverse perspectives to develop research-based solutions. In the Canadian health sector, this collaborative approach to research is often called integrated knowledge translation (IKT). This thesis is concerned with how boundaries are both essential and obstructive in IKT. While the goal of partnering is
openaire +1 more source
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim +4 more
wiley +1 more source
Engaging people with lived experience on advisory councils of a national not-for-profit: an integrated knowledge translation case study of Heart & Stroke Mission Critical Area Councils. [PDF]
Lewis KB +4 more
europepmc +1 more source
Developing translator's intercultural competence: a cognitive approach [PDF]
Muies, Larry, Yarosh, Maria
core +1 more source
Implantable optoelectrical devices are an effective resource for the modulation and monitoring of neural activity with high spatiotemporal resolution. This review discusses current challenges faced by these devices and outlines future perspectives for the development of next‐generation neural interfaces targeting chronic, multisite, and multimodal ...
Stella Aslanoglou +4 more
wiley +1 more source
Understanding barriers and identifying solutions for smoking cessation in primary care: survey results informed by an integrated knowledge translation approach in British Columbia, Canada. [PDF]
Simmons M +10 more
europepmc +1 more source
Using an integrated knowledge translation or other research partnership approach in trainee-led research: a scoping review protocol. [PDF]
Cassidy CE +11 more
europepmc +1 more source

