Results 201 to 210 of about 766,146 (274)

Professionalising the curriculum and increasing employability through authentic experienial learning : the cases of INSTB [PDF]

, 2017
Buysschaert, Joost, Fern´ndez-Parra, María, van Egdom, Gys-Walt   +2 more
core   +1 more source

Knowledge representation for data integration and exploration in translational medicine

, 2014
Biomedical research has evolved into a data-intensive science, where prodigious amounts of data can be collected from disparate resources at any time. However, the value of data can only be leveraged through its analysis, which ultimately results in the acquisition of knowledge.
openaire   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Developing and planning country-specific integrated knowledge translation strategies: experiences from the GELA project in Malawi, Nigeria, and South Africa. [PDF]

BMC Public Health
Schmidt BM, Mabetha D, Chibuzor M, Kunje G, Arikpo D, Aquaisua E, Lakudzala S, Mbeye N, Effa E, Cooper S, Kredo T.   +10 more
europepmc   +1 more source

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Advanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode   +7 more
wiley   +1 more source

Supporting children's participation in active travel: developing an online road safety intervention through a collaborative integrated knowledge translation approach. [PDF]

Int J Qual Stud Health Well-being
Buttazzoni A, Pham J, Nelson Ferguson K, Fabri E, Clark A, Tobin D, Frisbee N, Gilliland J.   +7 more
europepmc   +1 more source

Purpose‐Adaptable Reinforced 3D Hyaluronic‐Acid Based Platform to Study Pathomechanisms of the Central Nervous System

Advanced Healthcare Materials, EarlyView.
Platform system to create biofabricated 3D spinal cord tissue models: Combining high resolution PCL fiber placement, a customized, hyaluronic acid‐based hydrogel, two cell types (spinal cord neurons and astrocytes) together with three distinct laminin isoforms allow the formation of functional cell–cell network interactions.
Nicoletta Murenu, Esra Tuerker, Anna‐Lena Wiessler, Jessica Faber, Ievgenii Liashenko, Jeanette Weigelt, Jörg Tessmar, Paul D. Dalton, Sibylle Jablonka, Mateo S. Andrade Mier, Carmen Villmann, Silvia Budday, Natascha Schaefer   +12 more
wiley   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Designing and Developing Online Training for Diabetes Prevention Program Coaches Using an Integrated Knowledge Translation Approach: Development and Usability Study. [PDF]

JMIR Form Res
Cranston KD, Grieve NJ, Dineen TE, Jung ME.   +3 more
europepmc   +1 more source