Results 81 to 90 of about 3,719 (205)

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

open access: yesVIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf   +5 more
wiley   +1 more source

Evaluation of the Impact of Integrated Management System Implementation on Safety Performance Monitoring Indices in a Tile Industry

open access: yesطب کار, 2019
Introduction: Today, organizations need an integrated management system (IMS) to achieve global standards regarding the environment and employees. And one of the important goals of an integrated management system is to eliminate or reduce disasters to an
Rohollah Fallah   +4 more
doaj  

Developing A Maintenance Plan for An Automated Line by Integrating an Industrial Energy Management System (IMES)

open access: yesFiability and Durability
The increase in automation in modern production systems requires an integrated approach to maintenance and energy management, in order to maximize operational efficiency and reduce environmental impact. In this context, the article presents the development of a maintenance plan for an automated line, analyzed from the perspective of an Industrial ...
D. DUBIC   +3 more
openaire   +1 more source

Oxidative stress‐driven metabolic reprogramming defines two subtypes of cutaneous melanoma

open access: yesVIEW, EarlyView.
Cutaneous melanoma exhibits substantial molecular heterogeneity, and metabolic reprogramming may contribute to differences in tumor behavior and treatment response. In this study, we integrated multi‐omics data from SKCM cohorts to identify two metabolism‐associated subtypes with distinct oxidative stress profiles, immune microenvironments, prognostic ...
Qikun Gao, Ziyi Liu, Ying Xu
wiley   +1 more source

Análise da integração dos sistemas de gestão normalizados ISO 9001 e OHSAS 18001: estudo de casos múltiplos Analysis of the integration of normalized management systems ISO 9001 and OHSAS 18001: multiple case studies

open access: yesGestão & Produção, 2013
Para atender às demandas do ambiente, as organizações implementam diversos sistemas de gestão. Com isso, dificuldades relacionadas ao seu gerenciamento paralelo podem surgir, o que leva as empresas a integrar estes sistemas em um único Sistema de Gestão ...
Gislaine Aparecida Vitoreli   +1 more
doaj  

Consideration Without Economic Duress: Reframing the Analysis of Contractual Modifications

open access: yesThe Modern Law Review, EarlyView.
Prevailing approaches to the contractual enforceability of modifications revise or dispense with the requirement of consideration and invoke economic duress to rule out unfair, inequitable, or bad faith modifications. Enforceability turns effectively on the absence of economic duress. But economic duress is a doctrine of avoidance.
Peter Benson
wiley   +1 more source

The Wonder Years: A Demographic Approach to Revisit the Age‐at‐Size Conundrum in Amphibians

open access: yesIntegrative Zoology, EarlyView.
We combined repeated body size measurements of marked individuals of unknown age throughout their adult life with growth records of individuals marked as postmetamorphic juveniles and recaptured years later as sexually mature adults, focusing on 10 amphibian species in central Spain.
Gregorio Sánchez‐Montes   +5 more
wiley   +1 more source

Paradigm Shift in the Making? Geopolitical Challenges and Institutional Changes in the International Monetary System: From Neoliberalism to a Pluralist Multipolar Financial Order

open access: yesGlobal Policy, EarlyView.
ABSTRACT This paper examined the critical challenges facing the international monetary system, arguing that they have created conditions for a shift from a neoliberal framework to a pluralist multipolar financial order. Using an interdisciplinary approach that blends international law and international relations, the paper provides an analysis of the ...
Jiangyu Wang
wiley   +1 more source

Real‐world outcomes of ide‐cel and cilta‐cel in relapsed/refractory multiple myeloma: A nationwide, retrospective analysis in Austria

open access: yesBritish Journal of Haematology, EarlyView.
Summary B‐cell maturation antigen‐directed chimeric antigen receptor (CAR) T cells have revolutionized the treatment of relapsed/refractory multiple myeloma. However, no randomized head‐to‐head comparison of idecabtagene vicleucel (ide‐cel) and ciltacabtagene autoleucel (cilta‐cel) is available, and real‐world data suggest differences in efficacy and ...
Irene Strassl   +23 more
wiley   +1 more source

Machine-Learning-Guided Discovery of Boron-Free Narrowband Blue Thermally Activated Delayed Fluorescence Emitters. [PDF]

open access: yesAngew Chem Int Ed Engl
A data‐driven discovery engine—exhaustive enumeration of carbazole‐containing polycyclic aromatic hydrocarbons (Cz‐PAHs) followed by machine learning—identifies boron‐free, narrowband blue thermally activated delayed fluorescence emitters for organic light‐emitting diodes (OLEDs).
Hagai M   +6 more
europepmc   +3 more sources

Home - About - Disclaimer - Privacy