Results 161 to 170 of about 19,222,922 (285)

Position of water rescue service in integrated rescue system and rescuer training

open access: yes
Title: Position of the water rescue service in the Integrated Rescue System and rescuer training Objectives: The aim of this bachelor's thesis is to characterize the role and aktivity of the Water Rescue Service of the Czech Red Cross, which is among the
Filipovská, Zuzana
core   +1 more source

Fragile cooperation in high-casualty traffic incidents: a grounded theory study of inter-organizational emergency response in Iran. [PDF]

open access: yesBMC Public Health
Farzinnia B   +5 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

The 'Rule of Rescue' in Medical Priority Setting: Ethical Plausibilities and Implausibilities [PDF]

open access: yes
Not infrequently, the so-called Rule of Rescue gets invoked as an allegedly self-evident constraint to the CBE-goal of maximizing health benefit with a given health budget. In this paper this constraint is critically analyzed. It will be argued that some
Bettina Schoene-Seifert
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

IMOS - AusTemp - Sea Surface Temperature

open access: yes
Maintenance and Update Frequency: dailyStatement: See Technical description for details on the product generationStatement: In February 2026, the historical files of the product were created using the available SST products from IMOS (initial products ...

core  

Home - About - Disclaimer - Privacy