MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Integrated Biorefineries for Food Waste and Food-Processing Side Streams Through Feedstock-Oriented Design and Sustainable Process Integration. [PDF]
Lazăr Coșbuc ED +4 more
europepmc +1 more source
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
A culturally synergetic approach to international Human Resource Management: implementing an integrated approach. [PDF]
An integrated approach to IHRM tries to create a HRM system with substantial global integration combined with local differentiation. How to successfully implement such an integrated IHRM approach is the focus of this paper. The literature indicates three
Janssens, Maddy
core
Targeting environmental determinants and settlements in public health planning for the containment of visceral leishmaniasis: a One Health perspective. [PDF]
Shrivastava SR +6 more
europepmc +1 more source
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source
Shaping the Future of Pharmacology Education: Emerging Directions and International Initiatives From the Seventh International Union of Basic and Clinical Pharmacology Education Satellite Meeting. [PDF]
Guilding C +13 more
europepmc +1 more source
ASSESSMENT OF SUPPLIERS OF MATERIAL RESOURCES WITH INTEGRAL INDICATOR
N. B. Orlova, I. A. Larionova
openaire +2 more sources
Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi +6 more
wiley +1 more source
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page +4 more
wiley +1 more source

