Results 71 to 80 of about 44,724 (245)

Integration of Production Planning and Scheduling Based on RTN Representation under Uncertainties

Algorithms, 2019
Production planning and scheduling are important bases for production decisions. Concerning the traditional modeling of production planning and scheduling based on Resource-Task Network (RTN) representation, uncertain factors such as utilities are rarely
Tao Zhang, Yue Wang, Xin Jin, Shan Lu
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Integrated Control and Scheduling [PDF]

, 1999
The report gives a state-of-the-art survey of the field of integrated control and scheduling. Subtopics discussed are implementation and scheduling of periodic control loops, scheduling under overload, control and scheduling co-design, dynamic task adaptation, feedback scheduling, and scheduling of imprecise calculations.
Årzén, Karl-Erik, Bernhardsson, Bo, Eker, Johan, Cervin, Anton, Persson, Patrik, Nilsson, Klas, Sha, Lui   +6 more
openaire   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Integrated Optimization of Production Scheduling and Explicit Model Predictive Control for Batch Process Based on SEN Framework

Liaoning Shiyou Huagong Daxue xuebao
Synchronous method is used to establish an integrated model for batch process production scheduling and control. In the scheduling section, a production scheduling model is established based on the State Equipment Network (SEN) and the unit⁃specific ...
Yue WANG, Xiaohui GUO, Yuting JIN, Xin JIN   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Research and Application of Auxiliary Optimization Technology of Power Grid Accident Processing Based on the Mode of Regulation and Control Integration

MATEC Web of Conferences, 2015
Accident processing is the most important link of the scheduling of daily monitoring. The improvement of intelligent level is of great significance for improving the efficiency of accident processing scheduling, shortening the time of accident processing
Cui Houzhen, Qin Jun, Wu Dongya, Du Xiaoyong   +3 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Machine learning based integrated scheduling and rescheduling for elective and emergency patients in the operating theatre. [PDF]

Ann Oper Res, 2023
Eshghali M, Kannan D, Salmanzadeh-Meydani N, Esmaieeli Sikaroudi AM.   +3 more
europepmc   +1 more source