Results 71 to 80 of about 63,403 (312)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Planning for the integrated refinery subsystems [PDF]

open access: yes, 2012
In global energy and industrial market, petroleum refining industry accounts for a major share. Through proper planning and the use of adequate mathematical models for the different processing units, many profit improving opportunities can be realized ...
Ejikeme-Ugwu, Edith
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Integral Approaches to Integrated Scheduling

open access: yes, 2007
integration to achieve computational performance. We reconsider the widely used models and representations for production scheduling problems, we review optimization objectives and we discuss and propose efficient solution approaches to the production scheduling problem.
openaire   +2 more sources

Integrating scheduling policies into workflow engines

open access: yesProcedia Computer Science, 2010
AbstractWorkflow applications running on distributed environments are a promising solution for resource and computing intensive problems. However, the heterogeneity of resources in these kind of environments may turn scheduling of such applications into a complicated enterprise.
Gustavo Martínez   +2 more
openaire   +1 more source

Sleep Scheduling with Expected Common Coverage in Wireless Sensor Networks [PDF]

open access: yes, 2010
Sleep scheduling, which is putting some sensor nodes into sleep mode without harming network functionality, is a common method to reduce energy consumption in dense wireless sensor networks.
Korpeoglu, Ibrahim   +5 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Integrated Scheduling of Handling Equipment in Automated Container Terminal Considering Quay Crane Faults

open access: yesSystems
Quay cranes (QCs) play a vital role in automated container terminals (ACTs), and once a QC malfunctions, it will seriously affect the operation efficiency of ships being loaded and unloaded by the QC.
Taoying Li, Quanyu Dong, Xulei Sun
doaj   +1 more source

Integrated Production and Transportation Scheduling Method in Hybrid Flow Shop

open access: yesChinese Journal of Mechanical Engineering, 2022
The connection between production scheduling and transportation scheduling is getting closer in smart manufacturing system, and both of those problems are summarized as NP-hard problems.
Wangming Li   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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