Results 61 to 70 of about 49,493 (257)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Energy harvesting assisted UAV sensing integrated system resource allocation

open access: yesWireless Power Transfer
In the context of the deep integration of wireless communication and perception technology, this paper examines the resource allocation problem of an energy harvesting-assisted unmanned aerial vehicle (UAV) communication and perception integrated systems.
Guangjun Liang   +3 more
doaj   +1 more source

Intelligent integrated sensing and communication: a survey

open access: yesScience China Information Sciences
Abstract Integrated sensing and communication (ISAC) is a promising technique to increase spectral efficiency and support various emerging applications by sharing the spectrum and hardware between these functionalities. However, the traditional ISAC schemes are highly dependent on the accurate mathematical model and suffer from the ...
Jifa Zhang   +6 more
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Robust Multi-Target Localization in ISAC Systems: Leveraging Multidimensional Scaling

open access: yesIEEE Open Journal of the Communications Society
Localization for multi-target systems (MTS) in anchor-free scenarios is receiving increasing attention, particularly for MTS, such as the Internet of Vehicles and swarms.
Ruhul Amin Khalil, Nasir Saeed
doaj   +1 more source

Planning Oriented Integrated Sensing and Communication

open access: yesCoRR
Integrated sensing and communication (ISAC) enables simultaneous localization, environment perception, and data exchange for connected autonomous vehicles. However, most existing ISAC designs prioritize sensing accuracy and communication throughput, treating all targets uniformly and overlooking the impact of critical obstacles on motion efficiency. To
Xibin Jin   +7 more
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Performance Analysis for Integrated Sensing and Communication Systems in Rainfall Scenarios

open access: yesAtmosphere
This paper investigates an integrated sensing and communication (ISAC) system operating in a rainfall scenario, where a base station (BS) simultaneously serves multiple communication users and performs rainfall detection.
Songtao Huang   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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