Results 101 to 110 of about 5,777,835 (305)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A national health information strategy for Malta [PDF]

open access: yes, 1993
In 1992 a national health information strategy was developed jointly by the Department of Health and the Information Systems Division. A detailed strategy study report was compiled, with recommendations for the development of a number of information ...
Agius Muscat, Hugo, Westwood, M.
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A Unique Case of Midvariant Reverse Takotsubo Cardiomyopathy

open access: yesCase Reports in Cardiology, 2018
Takotsubo cardiomyopathy, also known as stress cardiomyopathy, is known to have 4 variants: apical, midventricular, basal, and focal. Here, we report the 2nd case of reverse midvariant (midventricular) stress cardiomyopathy and the 1st case of reverse ...
Carmel Moazez   +2 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The Planar Core–Shell Junctionless MOSFET

open access: yesMicromachines
The core–shell junctionless MOSFET (CS-JL FET) meets the process requirements of FD-SOI technology. The transistor body comprises a heavily doped ultrathin layer (core linking the source and the drain), located underneath an undoped layer (shell).
Cunhua Dou   +14 more
doaj   +1 more source

An Integrated Content and Metadata based Retrieval System for Art

open access: yes, 2004
In this paper we describe aspects of the Artiste project to develop a distributed content and metadata based analysis, retrieval and navigation system for a number of major European Museums.
Abas, Fazly S   +9 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

A selection principle of submodule switching state vectors for switching frequency reduction in voltage self‐balancing half‐bridge modular multilevel converters

open access: yesIET Power Electronics
The problem of submodule switching frequency reduction in half‐bridge modular multilevel converters (HB‐MMCs) with capacitor voltage self‐balancing control is considered and explored in this paper.
Yiyuan Zhou   +4 more
doaj   +1 more source

Rotational Doppler Signal Classification Based on Support Vector Machine

open access: yesPhotonics
The rotational Doppler effect (RDE) has been playing a vital role in the detection of rotational motion in recent years. However, the results obtained from this detection method are easily influenced by the detection conditions.
Song Qiu, Jin Zheng, Minghui Xiong
doaj   +1 more source

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