Results 181 to 190 of about 2,043,487 (317)

Development and Validation of an AI-Integrated System for Automated Fracture Detection and Pedicle Puncture Planning in Lumbar Osteoporotic Vertebral Compression Fractures Based on the Nine-Grid Area Division Method. [PDF]

Orthop Surg
Zuo W, Xie Y, Meng H, Liu D, Yuan S, Song J, Lei X, Liu X, Zhang Y, Zang L, Ding L, Zhang L, Fei Q.   +12 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

IMOS - Deep Water Moorings - Deep Water Arrays (DA) Sub-facility, Totten array, Totten2 Mooring Platform

Maintenance and Update Frequency: asNeeded<b>Credit</b><br/>Australia’s Integrated Marine Observing System (IMOS) is enabled by the National Collaborative Research Infrastructure Strategy (NCRIS).

core  

A streamlined integrated system integrating lysate release, freeze-dried reagents for multiplex polymerase chain reaction, and intelligent analysis for TORCHes pathogen identification. [PDF]

Front Microbiol
Fu M, He S, Wu Y, Mao S, Chen W, Zhang N, Chen X, Wang J, Zhou L, Xi X, Wu J, Wang H, Ma Y.   +12 more
europepmc   +1 more source

Integrated Information Systems [PDF]

Yearbook of Medical Informatics, 2000
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

IMOS - Deep Water Moorings - Deep Water Arrays (DA) Sub-facility, Totten array, Totten1 Mooring Platform

Maintenance and Update Frequency: asNeeded<b>Credit</b><br/>Australia’s Integrated Marine Observing System (IMOS) is enabled by the National Collaborative Research Infrastructure Strategy (NCRIS).

core  

Complications of Endoscopic Pressure Study Integrated System: Review of 1205 Cases in 10 Years' Experience. [PDF]

DEN Open
Iwasaki M, Tanaka I, Inoue H, Saino M, Ushikubo K, Yamamoto K, Nishikawa Y, Owada K, Abiko S, Tanabe M.   +9 more
europepmc   +1 more source

Integrated System Built for Small-Molecule Semiconductors via High-Throughput Approaches. [PDF]

J Am Chem Soc, 2023
Wu J, Zhang J, Hu M, Reiser P, Torresi L, Friederich P, Lahn L, Kasian O, Guldi DM, Pérez-Ojeda ME, Barabash A, Rocha-Ortiz JS, Zhao Y, Xie Z, Luo J, Wang Y, Seok SI, Hauch JA, Brabec CJ.   +18 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source