Results 171 to 180 of about 4,583,135 (309)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Digital integrated systems in primary health care: advancing universal health coverage in low- and middle-income countries. [PDF]

EBioMedicine
Ashrafizadeh H, Rassouli M.
europepmc   +1 more source

Analysis of a Four-Component Competing Endogenous RNA Network Reveals Potential Biomarkers in Gastric Cancer: An Integrated Systems Biology and Experimental Investigation. [PDF]

Adv Biomed Res, 2023
Salehi-Mazandarani S, Nikpour P.
europepmc   +1 more source

Humidtropics: Report on the Inaugural Meeting of the Independent Advisory Committee [PDF]

, 2015
CGIAR Research Program on Integrated Systems for the Humid Tropics
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Publisher Correction: Single neuromorphic memristor closely emulates multiple synaptic mechanisms for energy efficient neural networks

Nature Communications
Christoph Weilenmann, Alexandros Nikolaos Ziogas, Till Zellweger, Kevin Portner, Marko Mladenović, Manasa Kaniselvan, Timoleon Moraitis, Mathieu Luisier, Alexandros Emboras   +8 more
doaj   +1 more source

Textile Hybrid Electronics for Multifunctional Wearable Integrated Systems. [PDF]

Research (Wash D C)
Cai Z, Ye K, Luo H, Tang J, Yang G, Xie H, Yang H, Xu K.   +7 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Construction and applications of exosome-microneedle integrated systems. [PDF]

Int J Pharm X
Zheng L, Sun J, Wang L, Ding Z, Tang Y, Dai M, Tang H.   +6 more
europepmc   +1 more source

HYGIEIA: HYpothesizing the Genesis of Infectious Diseases and Epidemics through an Integrated Systems Biology Approach. [PDF]

Viruses, 2022
Ward B, Yombi JC, Balligand JL, Cani PD, Collet JF, de Greef J, Dewulf JP, Gatto L, Haufroid V, Jodogne S, Kabamba B, Pyr Dit Ruys S, Vertommen D, Elens L, Belkhir L.   +14 more
europepmc   +1 more source