Results 131 to 140 of about 35,067 (308)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Inversion of an integral transform [PDF]

open access: yesProceedings of the American Mathematical Society, 1958
Pollard, Harry, Widom, Harold
openaire   +2 more sources

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Improvement of Power Transformer Insulation Diagnosis Using Oil Characteristics Data Preprocessed By SMOTEBoost Technique

open access: yes, 2014
This paper proposes a novel method for power transformer insulation assessment using oil characteristics. A hybrid algorithm, named as SMOTEBoost is implemented in the paper to improve the diagnosis accuracy and consistency.
Ma, Hui, Saha, Tapan, Cui, Yi
core   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Design and Analysis of Integrated Planar Transformer for LLC Converter

open access: yes, 2018
Planar Magnetics is replacing conventional magnetic structures in many applications. Especially Planar transformers are good choice for applications requiring integrated magnetics.
Gurusamy, Vigneshwaran
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Automated simulation setup in HFSS for on-chip transformer

open access: yes, 2010
This report aims to provide a comprehensive review of the Final Year Project, Automated Simulation Setup in High Frequency Structure Simulator (HFSS) for On-Chip Transformer, which pertains to the investigation and design of silicon-based spiral on-chip ...
Tan, Bennett Chin Hin.
core  

Integrated higher-order pulse-width modulation filter-transformer structure for single-phase static compensator

open access: yes, 2013
A power filter is necessary to connect the output of a power converter to the grid so as to reduce the harmonic distortion introduced in the line current and voltage by the power converter.
Venkatramanan, D, John, Vinod
core   +1 more source

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