Results 131 to 140 of about 5,531,966 (305)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Using exploratory factor analysis in information system (IS) research [PDF]

, 2011
This paper is part of a field study that explored the impact of Information System implementation on Organisational Performance by examining the concept of IS effectiveness and by exploring how businesses arrive at the conclusion that the undertaking is ...
Koufopoulos, DN, Nikas, A, Argyropoulou, M   +2 more
core  

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Integrating pedagogy and technology : improving teaching and learning in higher education /

, 2015
Comprend des références bibliographiques et un index.Integrating Teaching and Technology: A Matrix for Professional Faculty Development provides college faculty and administrators with the foundations for a new model for integrating the two most critical
Tomei, Lawrence A., Bernauer, James A.
core   +1 more source

Optimized integrating factor technique for Schr\"odinger-like equations

, 2023
The integrating factor technique is widely used to solve numerically (in particular) the Schr\"odinger equation in the context of spectral methods. Here, we present an improvement of this method exploiting the freedom provided by the gauge condition of ...
Clamond, D, Marcos, B, Lovisetto, Martino   +2 more
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Integrating geochemical indices and factor analysis to identify trace metal sources in the Mathur watershed

Discover Geoscience
The geochemical impacts of monsoon cycles and human activities on trace element concentrations represent a critical gap in environmental knowledge for specific regional watersheds. While seasonal influences on groundwater quality are generally understood,
Arjun Peethambaran, M. A. Anso, T. S. Salumol, A. Shanmugasundharam, Roja Mary Joseph, V. Sanija   +5 more
doaj   +1 more source

OPTIMIZED INTEGRATING FACTOR TECHNIQUE FOR SCHRÖDINGER-LIKE EQUATIONS

, 2021
The integrating factor technique is widely used to solve numerically (in particular) the Schrödinger equation in the context of spectral methods. Here, we present an improvement of this method exploiting the freedom provided by the gauge condition of the
Clamond, D, Marcos, B, Lovisetto, Martino   +2 more
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source