Results 201 to 210 of about 8,918,506 (303)

A content analysis of global and national policies, plans, and guidelines to integrate NCDs with HIV care in LMICs. [PDF]

PLOS Glob Public Health
Kapur R, Briggs A, Moinul D, Giorgadze T, Alvarez GG, Namusisi KN, Purtle J, Armstrong-Hough M, Shelley D.   +8 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Barriers and Enablers to Integrating Patient-Generated Health Data in Shared Decision-Making From Health Care Professional and Patient Perspectives: Scoping Review. [PDF]

JMIR Mhealth Uhealth
V S Pakianathan P, Kumar D, Prabath J, Hussein R, Niebauer J, Schmidt A, Smeddinck J.   +6 more
europepmc   +1 more source

Three year intervention on risk factors for atherosclerosis in the italian nine communities study

, 1986
ARCA, Marcello, The Research Group for Atherosclerosis Risk Factors   +1 more
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Tumor Exposomics: A New Paradigm for Individualized Continuous Exposure Monitoring. [PDF]

Adv Sci (Weinh)
Shen K, Wang W, Wang Y, Wu Y, Liu X, Zhang W, Ou J.   +6 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Integrating ChatGPT to support children and adolescents with diabetes mellitus in South African healthcare: Perspectives of healthcare professionals and academics. [PDF]

Afr J Prim Health Care Fam Med
Chuma KG, Sibiya PT.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source