Results 201 to 210 of about 1,601,500 (267)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Heterogeneity of HTLV-1 proviral integration sites and internal structures in the ATL cell line MT-1. [PDF]

Hum Cell
Izaki M, Hashikura Y, Umekita K, Umeki K, Miyazaki T.   +4 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Education Research: Integration of Trainee and Faculty Clinics at an Academic Medical Center: Improving Quality of Care and Education. [PDF]

Neurol Educ
Schelke M, Cai AC, Cioroiu C, Dababneh D, Negrutiu M, Montealegre NC, Perez-Caro J, Bell M, Kleyman I, Roberts K, Mayeux R, Williams OA.   +11 more
europepmc   +1 more source

Ethical Governance of Large Language Models in Health Care: Trust, Responsibility, and Equity in Routine Use. [PDF]

J Med Internet Res
Yang X, Xu C.
europepmc   +1 more source

Positioning HIV SMRTcap within the HIV reservoir toolbox. [PDF]

PLoS Pathog
Loddo A, Delobel P, Vellas C.
europepmc   +1 more source

Strengthening trauma care in South Africa: Tier 1 integration of emergency first aid responder (EFAR) programmes with emergency medical services. [PDF]

Afr J Emerg Med
Abdullah N, De Vos S, Slingers M, Hendrikse C, Geduld H.   +4 more
europepmc   +1 more source