A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
ASEAN: perspectives on economic integration: keynote address: enhancing competitiveness through regional integration [PDF]
Pitsuwan, Surin
core
Opportunities and barriers arising from the COVID-19 pandemic for health campaign integration across immunizations, neglected tropical diseases, insecticide-treated bed nets, and vitamin A supplementation: A qualitative key informant interview study. [PDF]
Krentel A +8 more
europepmc +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
The Journey from Employment to Alignment: Hospital System Acquisition of Physician Groups. [PDF]
Dapaah-Afriyie K.
europepmc +1 more source
Exam‐level analysis of lecture capture viewing and student exam performance
This study asks how lecture capture relates to exam performance in biology courses with three noncumulative exams. Mixed‐effects modeling separated between‐students from within‐student effects on exam %. Students who watched more recordings earned higher grades, but viewing spikes above a student's own mean, consistent with cramming, predicted small ...
Kirk Hillsley
wiley +1 more source
Elucidating Alterations in Viral and Human Gene Expression Due to Human Papillomavirus Integration by Using Multimodal RNA Sequencing. [PDF]
Tamai K +14 more
europepmc +1 more source
Repeat-element RNAs integrate a neuronal growth circuit
Eitan Erez Zahavi +31 more
openalex +2 more sources
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Correction: Physical Status of Human Papillomavirus Integration in Cervical Cancer Is Associated with Treatment Outcome of the Patients Treated with Radiotherapy. [PDF]
Shin HJ, Joo J, Yoon JH, Yoo CW, Kim JY.
europepmc +1 more source

