Glycosylation Gene Signatures as Prognostic Biomarkers in Glioblastoma
ABSTRACT Objective Glioblastoma (GBM) is an aggressive brain tumor characterized by significant heterogeneity. This study investigates the role of glycosylation‐related genes in GBM subtyping, prognosis, and response to therapy. Methods We analyzed mRNA expression data and clinical information from The Cancer Genome Atlas (TCGA) and Gene Expression ...
Tong Zhao+4 more
wiley +1 more source
Timed chromatin invasion during mitosis governs prototype foamy virus integration site selection and infectivity. [PDF]
Lagadec F+8 more
europepmc +1 more source
CSF Biomarker‐Based Cognitive Trajectories in Parkinson's Disease‐Subjective Cognitive Decline
ABSTRACT Objective Cognitive complaints without objective cognitive impairment in Parkinson's Disease, termed Parkinson's Disease‐Subjective Cognitive Decline (PD‐SCD), have been associated with cognitive decline. However, its progression is heterogeneous, highlighting the need for improved identification of patients at greater risk for deterioration ...
Jon Rodriguez‐Antiguedad+7 more
wiley +1 more source
A Unified Framework for Alzheimer's Disease Knowledge Graphs: Architectures, Principles, and Clinical Translation. [PDF]
Dobreva J+4 more
europepmc +1 more source
Translating Muscle RNAseq Into the Clinic for the Diagnosis of Muscle Diseases
ABSTRACT Objective Approximately half of patients with hereditary myopathies remain without a definitive genetic diagnosis after DNA next‐generation sequencing (NGS). Here, we implemented transcriptome analysis of muscle biopsies as a complementary diagnostic tool for patients with muscle disease but no definitive genetic diagnosis after exome ...
Alba Segarra‐Casas+24 more
wiley +1 more source
Editorial: Exploring the power of AI and ML in smart grids: advancements, applications, and challenges. [PDF]
Kulkarni V+4 more
europepmc +1 more source
Actionable Wearables Data for the Neurology Clinic: A Proof‐of‐Concept Tool
ABSTRACT Objective Wearable devices can monitor key health and fitness domains. In multiple sclerosis (MS), monitoring step count and sleep is feasible, valid, and offers a holistic glimpse of patient functioning and worsening. However, data generated from wearables are typically unavailable at the point of care.
Nicolette Miller+12 more
wiley +1 more source
Bioinspired enamel repair via inorganic ionic polymerization using calcium phosphate ionic clusters and nano-hydroxyapatite. [PDF]
Elkhouly MA+4 more
europepmc +1 more source