Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Textile Radio-Frequency Active Devices and Systems: Wireless Communication and Energy Harvesting. [PDF]
Song W +7 more
europepmc +1 more source
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Beyond individual skill: How school innovation climate amplifies the pathway from Generative AI Adoption to deep pedagogical integration. [PDF]
Dong T, Kong Y, Chen R, Yang Z.
europepmc +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Scaling medical-dental integration nationally: outcomes from the MORE Care initiative. [PDF]
Vermillion M +7 more
europepmc +1 more source
From Representation to Integration: Lived Experience in Mental Health Teams: A Qualitative Descriptive Study. [PDF]
Hatchman O +4 more
europepmc +1 more source
Representation and Utilization of Laboratory Data in CT-Based Acute Abdominal Emergency Radiology: A Methodological Content Analysis. [PDF]
Tiryaki Baştuğ B, Güney T.
europepmc +1 more source
Rapid invisible frequency tagging (RIFT) does not evoke intermodulation components in the neural response. [PDF]
Zhigalov A, Jensen O.
europepmc +1 more source

