Results 261 to 270 of about 7,800,417 (330)

Evolution of the HIV-1 integration site landscape and inducible reservoir in early-treated people. [PDF]

PLoS Pathog
Struyve T, Pardons M, De Clercq J, Termote L, Lambrechts L, Noppe Y, Lichterfeld M, Rutsaert S, Vandekerckhove L.   +8 more
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Exploring the state and drivers of community integration for older adults in China: insights from a social ecosystem perspective. [PDF]

BMC Public Health
Wang J, Zhou W, Xu L, Xie X, Wang Y, Qin X, Zheng L, Wang L.   +7 more
europepmc   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Evaluation of the Effectiveness of Close-Knit Medical Alliances on the Integration of HIV Prevention and Treatment in County-Level Areas in China: Protocol for a Delphi Study.

JMIR Res Protoc
Du S, Liu Y, Luo Q, Dai R, He J, Yang Y, Yang Y.   +6 more
europepmc   +1 more source

Supporting Clinical Identification of Children with Sensory Integration Challenges: A Decision Guide for Primary Care Providers. [PDF]

Brain Sci
Lane SJ, Schoen SA, Schaaf R, Bundy A, Mailloux Z, Roley SS, May-Benson TA, Parham LD.   +7 more
europepmc   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

From Suppression to Integration: A Self-Determination Theory Perspective on Emotion Regulation in Medical Education. [PDF]

Clin Teach
Neufeld A.
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Integration field-based breadth-first search for flow field pathfinding. [PDF]

Sci Rep
Yang J, Chen X, Dong M.
europepmc   +1 more source