Results 131 to 140 of about 11,479,686 (309)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Supply chain resource integration method under 4PL mode based on associated data
The relevance of power supply chain resources is a key factor affecting the hit rate of resource integration. Therefore, a 4PL mode based supply chain resource integration method based on associated data is proposed. Firstly, analyze the functions of the
Huayu Chu +5 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The policies and decisions of association and economic integration of the Republic of Moldova into the European economic social system have a pseudo-scientific, contradictory, fragmentary character.
Gheorghe Rusu +2 more
doaj
BackgroundThe prevalence of cognitive impairment among older adults remains high. It has been proven that social integration is related to cognitive function.
Amu Mose +4 more
doaj +1 more source
Contour integrals associated differential equations
For any n contour integrals y=cos^n^+^[email protected]?"Ccosh(zs)(sinz-sinx)^n^+^1dz,y=sin^n^+^[email protected]?"Ccosh(zs)(cosz-cosx)^n^+^1dz,s^[email protected], and their associated second-order ordinary differential equations which are not studied are given. Complete solution is given by calculating residues for n=1.
openaire +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The joint conference proceedings from the 1960 American Library Association and Canadian Library Association Conference at Montreal, Quebec, June 19 ...
American Library Association +1 more
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