Results 91 to 100 of about 166,506,875 (338)

MAPS AND FLOOR PLANS ENHANCED 3D MOVEMENT MODEL FOR PEDESTRIAN NAVIGATION [PDF]

, 2009
A model that realistically imitates real pedestrian movement can be used for numerous applications such as infrastructure design, evacuation planning, architecture, robot-human interaction or navigation.
Kaiser, Susanna, Khider, Mohammed, Robertson, Patrick, Angermann, Michael   +3 more
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Impacts of global navigation satellite system jamming on aviation

Global navigation satellite systems have enabled significant improvements in aeronautical navigation. However, in recent years, a growing number of interference events have been reported by flight crews. In this paper, we first identify such events using
Olive, Xavier, Felux, Michael, Waltert, Manuel, Figuet, Benoit, Fol, Patric   +4 more
core   +1 more source

Spatial representations of place cells in darkness are supported by path integration and border information

Frontiers in Behavioral Neuroscience, 2014
Effective spatial navigation is enabled by reliable reference cues that derive from sensory information from the external environment, as well as from internal sources such as the vestibular system.
Sijie eZhang, Fabian eSchoenfeld, Laurenz eWiskott, Denise eManahan-Vaughan   +3 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

How do humans navigate in the virtual lunar environment?

Geo-spatial Information Science
Exploring navigation strategies in lunar environment contributes to understanding the unique navigation mechanism of humans in extraterrestrial environments. However, it is unclear whether human navigation strategies in lunar environments are the same as
Bowen Shi, T. Qin, B. He, L. Mu, W. Dong
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Optimal multiguidance integration in insect navigation [PDF]

Proceedings of the National Academy of Sciences, 2018
Significance The discovery of “place cells,” “grid cells,” and other spatial cells in the rodent’s forebrain has strengthened the idea that animals navigate their home range environments thanks to a “cognitive map.” Tiny-brained insects, like bees, are also thought to use such a centralized metric mental representation.
Thierry Hoinville, Rüdiger Wehner
openaire   +3 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source