Results 131 to 140 of about 2,948,600 (354)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Comparative Institutional and Political Analysis of the European and Eurasian Integration

open access: yesУправленческое консультирование, 2018
The purpose of this article is to identify common and distinctive characteristics and features of the European and Eurasian integration, the political system and political institutions of the legal entities - European Union (EU) and Eurasian Economic ...
Yana Glittova, Yury Vasilyevich Kosov
doaj  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

THE DEVELOPMENT OF THE FUEL AND ENERGY COMPLEX OF UKRAINE UNDER CONDITIONS OF GLOBALIZATION AND INTERNATIONAL INTEGRATION [PDF]

open access: yes, 2013
The aim of the article is an attempt to generalize and analyze the role, place and mechanisms of developing economic behavior of Ukraine’s fuel and energy complex subjects on the way to the world processes of globalization and international ...
Didyk, Liudmyla, Lisovenkova, Irina
core  

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Integrating testing techniques through process programming [PDF]

open access: bronze, 1989
Debra J. Richardson   +2 more
openalex   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Evaluation and recommendations for work group integration within the Materials and Processes Lab [PDF]

open access: yes
The goal of this study was to evaluate and make recommendations for improving the level of integration of several work groups within the Materials and Processes Lab at the Marshall Space Flight Center.
Farrington, Phillip A.
core   +1 more source

Designing Information System To Support Business Process Improvement In A Small-Mid Size Bottled Drinking Water Industry [PDF]

open access: yes, 2008
Due to inefficiencies of the business processes in small-mid size of bottled drinking water industries, it is necessary to improve them. The improvements are carried out in business processes of production, warehouse, delivery, marketing, and finance
Hisjam, Muh.   +2 more
core  

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