Results 131 to 140 of about 574,564 (319)

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

Process and material handling models integration [PDF]

open access: bronze, 1999
Michael A. Norman   +5 more
openalex   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

ПОДГОТОВКА СПЕЦИАЛИСТОВ БИБЛИОТЕЧНОГО ДЕЛА СИСТЕМЫ СПО В КОНТЕКСТЕ СОЦИОКУЛЬТУРНОГО РАЗВИТИЯ НЕБОЛЬШИХ ГОРОДОВ (на примере г. Канска Красноярского края)

open access: yesБиблиосфера, 2011
The modern social and cultural situation in a removed town Kansk and the role of the Krasnoyarsk Regional Library School in training of specialists in the field of culture are described.

doaj  

Process Design & Integration of Salicide and Source/Drain process Modules for Improved Device Performance [PDF]

open access: bronze, 1998
Pushkar P. Apte   +7 more
openalex   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

Globalization processes and their impact on library activity

open access: yesБиблиосфера, 2015
The current stage of society development is conditioned by the intense globalization processes, during which the local culture integration with the world international environment takes place.
S. S. Araslanova
doaj  

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