Results 131 to 140 of about 704,715 (267)

Maturational Changes in Action-Effect Integration Processes Are Reflected by Changes in the Directed Cortical Network Communication. [PDF]

Hum Brain Mapp
Mayer J, Mückschel M, Hommel B, Beste C.   +3 more
europepmc   +1 more source

Generation of open biomedical datasets through ontology-driven transformation and integration processes. [PDF]

J Biomed Semantics, 2016
Carmen Legaz-García MD, Miñarro-Giménez JA, Menárguez-Tortosa M, Fernández-Breis JT.   +3 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Near-field terahertz time-domain spectroscopy for in-line electrical metrology of semiconductor integration processes for memory. [PDF]

Commun Eng
Jun S, Baek I, Park S, Choi EH, Yoon J, Jeon I, Jang Y, Priwisch M, Kim W, Kim S, Kim T, Jo T, Lee M, Ryu S, Koo N, Yang Y.   +15 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Conditional independence as a statistical assessment of evidence integration processes. [PDF]

PLoS One
Salinas E, Stanford TR.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Distinct oscillatory patterns differentiate between segregation and integration processes in perceptual grouping. [PDF]

Hum Brain Mapp
Costa GN, Schaum M, Duarte JV, Martins R, Duarte IC, Castelhano J, Wibral M, Castelo-Branco M.   +7 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

TRACK-a new algorithm and open-source tool for the analysis of pursuit-tracking sensorimotor integration processes. [PDF]

Behav Res Methods
Böttcher A, Adelhöfer N, Wilken S, Raab M, Hoffmann S, Beste C.   +5 more
europepmc   +1 more source