Results 161 to 170 of about 3,162,958 (354)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Nations and International Integration Processes
Köz-gazdaság, 2019 This paper is about the role and the future of the nation. They are analysed in the context of current development of international integration. The starting point is theoretical, which is based on the proposal of a more comprehensive, extended and ...
Tibor Palánkai
doaj
Linguistic Focus Promotes the Ease of Discourse Integration Processes in Reading Comprehension: Evidence From Event-Related Potentials. [PDF]
Front Psychol, 2018 Yang CL, Zhang H, Duan H, Pan H.
europepmc +1 more source
Minimum distance estimation of stationary and non-stationary ARFIMA processes [PDF]
A new parametric minimum distance time-domain estimator for ARFIMA processes is introduced in this paper. The proposed estimator minimizes the sum of squared correlations of residuals obtained after filtering a series through ARFIMA parameters.
Laura Mayoral
core
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Robot-Assisted Stair Climbing Training on Postural Control and Sensory Integration Processes in Chronic Post-stroke Patients: A Randomized Controlled Clinical Trial. [PDF]
Front Neurosci, 2019 Gandolfi M +10 more
europepmc +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Perceptual conflict during sensorimotor integration processes - a neurophysiological study in response inhibition. [PDF]
Sci Rep, 2016 Chmielewski WX, Beste C.
europepmc +1 more source
Integration of Business Process Data using Advanced ETL tools
, 2022 Ali Khebizi, Mourad HADJERİS
openalex +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source