Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
Generation of open biomedical datasets through ontology-driven transformation and integration processes. [PDF]
Carmen Legaz-García MD+3 more
europepmc +1 more source
Hepatocyte-Specific Mutation Establishes Retinoid X Receptor α as a Heterodimeric Integrator of Multiple Physiological Processes in the Liver [PDF]
Yu‐Jui Yvonne Wan+12 more
openalex +1 more source
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
Near-field terahertz time-domain spectroscopy for in-line electrical metrology of semiconductor integration processes for memory. [PDF]
Jun S+15 more
europepmc +1 more source
Reinforcement probability modulates temporal memory selection and integration processes. [PDF]
Matell MS, Kurti AN.
europepmc +1 more source
Phasewise numerical integration of finite element method applied to solidification processes [PDF]
Norberto M. Nigro+2 more
openalex +1 more source
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi+2 more
wiley +1 more source
Conditional independence as a statistical assessment of evidence integration processes. [PDF]
Salinas E, Stanford TR.
europepmc +1 more source