Results 251 to 260 of about 3,162,958 (354)

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Profiling digital technologies used to support the tuberculosis care cascade and their implementation across high burden countries: A systematic scoping review. [PDF]

Digit Health
Brubacher LJ, Oga-Omenka C, Beggs B, Bustos M, Heitkamp P, Morita PP, Dodd W.   +6 more
europepmc   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Prehospital blood transfusion coalition core competencies for emergency medical services personnel. [PDF]

Trauma Surg Acute Care Open
Krohmer J, O'Byrne H, Schaefer R, Bank EA, Holcomb JB, Bullock WJ, Hill RL, Levy M.   +7 more
europepmc   +1 more source

Integrating Process Safety and Process Security Risk Management: Practitioner Insights for a Resilience-Oriented Framework

Muhammad Firman Haiqal Mohd Rahim, Genserik Reniers, Ming Yang, Parthiban Siwayanan   +3 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Design and Application of Hetero-Multicomponent Metal Oxide Photocatalysts for Wastewater Treatment: Ti-Cu-Zn Catalysts and Future Research Directions. [PDF]

Molecules
Onoriode-Afunezie MO, Krutkevičius J, Šulčiūtė A.   +2 more
europepmc   +1 more source

Integrating video-game music into Electone pedagogy in China: investigating learning process and outcomes [PDF]

Jiachen Wei, Saifon Songsiengchai, Yaoping Liu, Tassanee Laknapichonchat   +3 more
openalex   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Frontoparietal Hubs Leverage Probabilistic Representations and Integrated Uncertainty to Guide Cognitive Flexibility. [PDF]

J Neurosci
Leach SC, Hollow H, Jiang J, Hwang K.
europepmc   +1 more source