Results 51 to 60 of about 574,564 (319)
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Process mapping and the integration of care
International Journal of Integrated Care, 2011 Introduction: The main objective of this work is to show how process mapping may contribute to the improvement of intraand interorganizational integration of care. Theory and methods: Under logic of service integration, quality of care depends not only on how the internal processes are implemented, but also on the quality of the transitions of care ...
Patrícia Redondo, Silvina Santana
openaire +6 more sources
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Integration with Stochastic Point Processes [PDF]
ACM Transactions on Graphics, 2016 We present a novel comprehensive approach for studying error in integral estimation with point distributions based on point process statistics. We derive exact formulae for bias and variance of integral estimates in terms of the spatial or spectral characteristics of integrands and first- and-second order product density measures of general point ...
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FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
Analysis of the foreign economic factors impact on the welfare of Ukrainians in the conditions of the world integration processes [PDF]
Marketing i Menedžment Innovacij, 2016 The aim of the article is to study and assess the impact of the foreign economic factors on the welfare of Ukrainian population in the conditions of Ukraine’s integration into the world community The results of the analysis. Ukraine’s integration to the
A.О. Simahova
doaj
An Integral Characterization of the Dirichlet Process [PDF]
Journal of Theoretical Probability, 2019 We give a new integral characterization of the Dirichlet process on a general phase space. To do so we first prove a characterization of the nonsymmetric Beta distribution via size-biased sampling. Two applications are a new characterization of the Dirichlet distribution and a marked version of a classical characterization of the Poisson-Dirichlet ...
openaire +3 more sources
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
The processes of identity integration
Filozofija i drustvo, 2009 Despite inevitable elusiveness of its meanings, explication of the persisting issues of identity remains the challenge for contemporary humans. Inability to achieve full insight into its complexity points to the need to corelate basic ideas as the essential way of self-cognition and self-awareness, which represent the meaning, value and the purpose of ...
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FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source