Results 91 to 100 of about 13,079,028 (312)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Nursing standard (Royal College of Nursing (Great Britain) : 1987), 2016 Last month, the National HIV Nurses Association (NHIVNA) produced guidelines on advanced nursing practice in HIV care, endorsed by the RCN.
Warriner, Jason, Croston, Michelle
openaire +2 more sources
Integration of FunKey Approach in SysML
2025 20th Annual System of Systems Engineering Conference (SoSE)This paper proposes a framework that integrates the previously introduced FunKey approach into a formal system modeling language to enhance early-stage architectural decision-making in systems engineering. FunKey links system functions to key drivers through a coupling matrix, emphasizing structured function allocation to improve system architecting ...
Zhao, Yiran, Bonnema, G. Maarten
openaire +1 more source
An Integral Approach to the Meaning of Competence
Vilnius University Open Series, 2020 Interest in the concept of competence is becoming crucial, as it is highly interconnected with the idea of life-long education and the requirement of continuing professional development. Improving competence and becoming a long-life learner are essential components of ensuring employability. From an educational perspective, a competence-based education
openaire +5 more sources
Polylinguality and Transcultural Practices, 2015 This article is dedicated to the statement of the problem of positive motivation shaping in the system of teaching Russian language and speech culture on the basis of differentiated approach, which provides the reliance on different educational levels of
Yu N Gosteva
doaj
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Liberal Arts & Integrative Studies
, 2014 Academic Program Review Self-Study Report for Liberal Arts & Integrative StudiesAcademic Program Review Self-Study Report for Liberal Arts & Integrative StudiesLiberal Arts & Integrative ...
BUS +2 more
core
Chapter 9 A Methodological Approach for Integrative Framing Analysis of Television News [PDF]
, 2018 This chapter lays out a set of procedures to investigate visual and verbal frames in news packages with an integrated approach. It provides an updated literature review on how audiovisual analyses can be conducted, reveals strengths and weaknesses of ...
Dan, Viorela
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source