Results 131 to 140 of about 13,079,028 (312)

ІНТЕГРАТИВНІ ТЕНДЕНЦІЇ РОЗВИТКУ ЗМІСТУ ГУМАНІТАРНОЇ ПІДГОТОВКИ МАЙБУТНІХ ІНЖЕНЕРІВ

open access: yesІнформаційні технології і засоби навчання, 2010
Головним напрямком на шляху вирішення заданої проблеми може бути інтегрування гуманітарних дисциплін у процес професійної підготовки фахівця технічного вузу в рамках системи безперервної гуманітарної освіти.
Olha He. Kaverina
doaj  

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

THE ROLE AND PLACE OF INTEGRATIVE APPROACH IN EDUCATIONAL SYSTEM [PDF]

open access: yes, 2020
The article is devoted to the integrative approach and its role, importance in the field of education in Uzbekistan. Besides, the possible perspectives achieved by using an integrative approach in all kinds of education system has been also taken into ...
Tursunboeva, Muxlisa Anvar qizi
core  

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Integrative approach of tomato fruit texture using multi-block analysis

open access: yes, 2012
Integrative approach of tomato fruit texture using multi-block analysis. 2.
Navez, Brigitte   +7 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Measurement validity and the integrative approach

open access: yes
Almaatouq et al. propose a novel integrative approach to experiments. We provide three examples of how unaddressed measurement issues threaten the feasibility of the approach and its promise of promoting commensurability and knowledge ...
Higgins, WC   +3 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Will and supervision in the context of further education seen from the integrative perspective

open access: yes, 2012
Die vorliegende Arbeit befasst sich mit Wille und Supervision im Weiterbildungskontext aus Integrativer Sicht. In einem ersten Schritt geht es um die Begriffsbestimmung von Wille sowie eine Beschreibung der Willensthematik aus evolutionsbiologischer ...
Rast-Pupato, Katharina, Kast, Esther
core   +1 more source

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