Results 31 to 40 of about 3,109 (287)

Elexacaftor-Tezacaftor-Ivacaftor: A Life-Changing Triple Combination of CFTR Modulator Drugs for Cystic Fibrosis

open access: yesPharmaceuticals, 2023
Cystic fibrosis (CF) is a potentially fatal monogenic disease that causes a progressive multisystemic pathology. Over the last decade, the introduction of CF transmembrane conductance regulator (CFTR) modulator drugs into clinical practice has profoundly
Mafalda Bacalhau   +5 more
doaj   +1 more source

EuroBioAct: new paths of integrative bioethics

open access: yes, 2017
EuroBioAct is a project under the Department of Social Sciences and Medical Humanities, Faculty of Medicine – University of Rijeka and the »Fritz Jahr« Documentation and Research Centre for European Bioethics at University of Rijeka.
Eterović, Igor, Doričić, Robert
core   +2 more sources

A Bioethical Reflection upon the Teaching-Learning Processes in Dentistry

open access: yesRevista Colombiana de Bioética, 2019
In this work, we reflect on the importance of teaching bioethics in the process of training dentistry students. Initially, a review of the literature referring to aspects related to the importance of bioethical training in dentistry is presented, and in ...
María Clara Rangel Galvis
doaj   +1 more source

Principlism in the daily practice of family medicine

open access: yesRevista Portuguesa de Medicina Geral e Familiar, 2021
Introduction: Principlism, from Tom Beauchamp and James Childress, is the most widely accepted theory in biomedical ethics. It is based on four principles: beneficence, non-maleficence, autonomy, and justice.
Ana Catarina Fortunato Silva   +3 more
doaj   +1 more source

APPROACHES TO THE CONCEPT OF VULNERABILITY FROM BIOETHICS: AN INTEGRATIVE REVIEW

open access: yes, 2022
20 páginasPara dar cuenta de la revisión integradora de literatura sobre el concepto de vulnerabilidad desde la bioética se analizó un corpus de 60 artículos publicados en español, inglés y portugués.
Valdez Fernández, Adriana Lucía   +3 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Life as the Medium of the Death? [PDF]

open access: yesIn Medias Res, 2019
The essay discusses a dialectical constellation of life and death phenomena in relation to the medium of beingness, in the context of the existential anxiety, which is commonly imposed as a "normal" state of the average inhabitant of the "globalistic ...
Luka Janeš
doaj  

BIOLOGICAL, PRODUCTIVE AND SOCIOCULTURAL IMPORTANCE OF HONEY BEES - CONTRIBUTION TO COMMON WELFARE [PDF]

open access: yesThe Holistic Approach to Environment
The coexistence of bees (Apis spp.) and humans goes back for millennia. Bees play an irreplaceable role as pollinators of flowering plants (Angiospermae) in ecosystems and thus in maintaining biodiversity.
Saša Zavrtnik   +3 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Atomic Layer Deposition Processes: Versatile Platforms for Engineering ZnO‐Chitosan Biointerfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
Vapour phase metalation (VPM), multiplied pulsed vapour phase infiltration (MPI), and O2 plasma‑enhanced atomic layer deposition (PEALD) tailor Zn–chitosan (Zn‑CS) films. PEALD improves wettability and biocompatibility. MPI enhances semiconductor behavior. Antiseptic selectivity: VPM → E. coli; MPI → H. pylori.
Mabel Moreno   +17 more
wiley   +1 more source

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