Results 31 to 40 of about 9,519,248 (257)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Comparative Roles of Mediators in Non-Litigation Dispute Resolution: Indonesia and Thailand

Jurnal USM Law Review
This study aims to comparatively analyze the role of mediators in non-litigation dispute resolution in Indonesia and Thailand and to examine how differences in legal and sociological orientations influence mediation effectiveness.
Abdulloh Tsani Harahap, Zainuddin Zainuddin   +1 more
doaj   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

Socio-Interactive Level of the Socialization of the Law as a Resulting Stage of the Law-Making Process

RUDN Journal of Law, 2018
The article analyzes a socio-interactive level of law socialization that is presented by the authors as a resulting stage of the legislative process, completing, in a sense, the formation of a legal rule.
Alla A Sokolova, Vasilii V Trofimov
doaj   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Integration of Scientific Literacy and Islamic Law in the Practice of in Vitro Fertilization (IVF)

Usraty
The integration of scientific literacy and Islamic law in the practice of In Vitro Fertilization (IVF) represents a complex convergence between biomedical innovation and religious ethical norms. This study investigates how IVF procedures—widely practiced
Ajrun 'Azhim Al As'hal, Ahmad Fauzi
doaj   +1 more source

THE EMERGENCE AND DEVELOPMENT OF THE THEORY OF SCIENTIFIC CRITICISM IN THE ENVIRONMENT OF REPRESENTATIVES OF RUSSIAN COOPERATION INTEGRATIVE UNDERSTANDING OF LAW AT THE BEGINNING OF XX S. (TO THE 150 ANNIVERSARY OF THE BIRTH OF N.I. PALIENKO AND TO THE 85 ANNIVERSARY OF THE DEATH OF A.S. YASHCHENKO) [PDF]

Северо-Кавказский юридический вестник, 2019
The article considers the formation of the foundations of scientific criticism in the environment of collaboration of prominent representatives of Russian legal thought.
Леусенко Дмитрий Александрович
doaj  

Dysregulated Cholesterol Metabolism, Chronic Inflammation, and Disability in Severe Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks, Mujeeb Shittu, Anna Wolska, Diala Ghazal, Bianca Weinstock‐Guttman, Alexander Burnham, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +8 more
wiley   +1 more source

How integrative modelling can break down disciplinary silos [PDF]

, 2013
This paper has been published in a peer-reviewed journal as: Kragt, M.E., Robson, B.J. & Macleod, C.J.A. (2013) Modellers’ roles in structuring integrative research projects. Environmental Modelling & Software, 39(1): 322-330. DOI: 10.1016/j.envsoft.2012.
Macleod, Christopher J.A., Robson, Barbara J., Kragt, Marit Ellen, Kragt, Marit E.   +3 more
core   +1 more source