Structural basis of Integrator-dependent RNA polymerase II termination
NatureThe Integrator complex can terminate RNA polymerase II (Pol II) in the promoter-proximal region of genes. Previous work has shed light on how Integrator binds to the paused elongation complex consisting of Pol II, the DRB sensitivity-inducing factor ...
Isaac Fianu +2 more
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Essential function of the integrator complex in Kaposi’s sarcoma-associated herpesvirus lytic replication [PDF]
Journal of VirologyThe integrator complex (INT) is an essential regulator of RNA biogenesis across evolution. Most current findings describe INT’s function in states of equilibrium, presenting a research gap in INT’s role in dynamic states, such as in infections and ...
Amy Nguyen +6 more
doaj +2 more sources
Genomic regulation of transcription and RNA processing by the multitasking Integrator complex
Nature Reviews Molecular Cell Biology, 2022 Alessandro Gardini
exaly +2 more sources
The Mediator complex: a central integrator of transcription
Nature Reviews Molecular Cell Biology, 2015 Dylan J Taatjes
exaly +2 more sources
Fast Sampling of Diffusion Models with Exponential Integrator [PDF]
International Conference on Learning Representations, 2022 The past few years have witnessed the great success of Diffusion models~(DMs) in generating high-fidelity samples in generative modeling tasks. A major limitation of the DM is its notoriously slow sampling procedure which normally requires hundreds to ...
Qinsheng Zhang, Yongxin Chen
semanticscholar +1 more source
A parallel rank-adaptive integrator for dynamical low-rank approximation [PDF]
SIAM Journal on Scientific Computing, 2023 This work introduces a parallel and rank-adaptive matrix integrator for dynamical low-rank approximation. The method is related to the previously proposed rank-adaptive basis update&Galerkin (BUG) integrator but differs significantly in that all arising ...
Gianluca Ceruti, J. Kusch, C. Lubich
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Differential effect of ubiquitous and germline depletion of Integrator complex function on C. elegans physiology [PDF]
Biology OpenBrandon M. Waddell +3 more
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An unconventional robust integrator for dynamical low-rank approximation [PDF]
BIT Numerical Mathematics, 2020 We propose and analyse a numerical integrator that computes a low-rank approximation to large time-dependent matrices that are either given explicitly via their increments or are the unknown solution to a matrix differential equation.
Gianluca Ceruti, C. Lubich
semanticscholar +1 more source
Regulation of expression of human RNA polymerase II-transcribed snRNA genes [PDF]
Open Biology, 2017 In addition to protein-coding genes, RNA polymerase II (pol II) transcribes numerous genes for non-coding RNAs, including the small-nuclear (sn)RNA genes.
Joana Guiro, Shona Murphy
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A Study of Digital Measurement and Analysis Technology for Transformer Excitation Magnetizing Curve
Energies, 2022 Transformer excitation magnetizing curves (TEMC) reflect the dynamic operation characteristics of iron-core materials. Using numerical analysis and the waveform recording function of digital oscilloscopes, we developed a cost-effective method for ...
Chien-Hsun Chen, Chih-Ju Chou
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