Results 101 to 110 of about 173,723 (292)

A single-board preprocessor and pulse generator [PDF]

open access: yes, 1986
The Aeronomy Lab. of NOAA has designed and built a single board, programmable radar controller for use with VHF ST (stratosphere troposphere) radars. The controller consists of a coherent integrator preprocessor and a radar pulse generator, both of which
Ayers, A. E.   +2 more
core   +1 more source

Signal Integrity and Power Integrity [PDF]

open access: yesIEEE Electromagnetic Compatibility Magazine, 2020
The COVID-19 pandemic has brought many changes. Among them, virtual conferences may become a new norm, or at least an important element for future technical symposia. Although we miss the opportunities to socialize with our colleagues and discuss issues face-to-face, virtual conferences can present different, yet still enjoyable, experiences and allow ...
openaire   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Adaptive Integration and Improper Integrals [PDF]

open access: yesMathematics of Computation, 1975
Let R be the class of all functions that are properly Riemann-integrable on [0, 1], and let IR be the class of all functions that are properly Riemann-integrable on [a, 1] for all a > 0 a > 0 and for which \[ lim a →
openaire   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

INTEGRATION OF PARTIALLY INTEGRABLE EQUATIONS [PDF]

open access: yesWaves and Stability in Continuous Media, 2006
12 p, WASCOM XIII (Acireale, 19-25 June 2005)
openaire   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

The role of pallidum in the neural integrator model of cervical dystonia

open access: yesNeurobiology of Disease, 2019
Dystonia is the third most common movement disorder affecting three million people worldwide. Cervical dystonia is the most common form of dystonia. Despite common prevalence the pathophysiology of cervical dystonia is unclear.
Alexey Sedov   +8 more
doaj   +1 more source

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