Results 101 to 110 of about 4,811,697 (360)
Integrator orchestrates RAS/ERK1/2 signaling transcriptional programs
In this study, Yue et al. describe a new role for the RNAPII-associated complex Integrator in MAPK signaling. They show that Integrator mediates the transcriptional responsiveness following growth factor signaling, that depletion of Integrator can ...
Jingyin Yue +5 more
semanticscholar +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Проблема деиндустриализации в экономике России
Author analyzes background and consequences of deindustrialization in the USA and the Russian Federation. Analysis ofhistorical background shows that solutions for negative factors of deindustrialization are connected with competent understanding of ...
S. V. Firsov
doaj
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
The Integration Strategy of Ideological and Political Teaching and Traditional Culture in Universities Under the Background of Informatization [PDF]
WANG Na, YE Xinghuo
openalex +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
This paper studies the consensus problem of multiagent system with packet losses and communication delays under directed communication channels. Different from previous research results, a novel control protocol is proposed depending only on periodic ...
Zheping Yan, Di Wu, Wei Zhang, Yibo Liu
doaj +1 more source
Generalized Fractional-Order Discrete-Time Integrator
We investigate a generalization of discrete-time integrator. Proposed linear discrete-time integrator is characterised by the variable, fractional order of integration/summation.
D. Mozyrska, P. Ostalczyk
semanticscholar +1 more source
Signal Integrity and Power Integrity [PDF]
The COVID-19 pandemic has brought many changes. Among them, virtual conferences may become a new norm, or at least an important element for future technical symposia. Although we miss the opportunities to socialize with our colleagues and discuss issues face-to-face, virtual conferences can present different, yet still enjoyable, experiences and allow ...
openaire +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source

