Results 41 to 50 of about 313,330 (307)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

On the Sufis’ Intellect-aversion [PDF]

open access: yesحکمت اسرا, 2012
In a part of mystical literature, as well as the words of some individuals affiliated with mysticism, intellect and mysticism have been portrayed as being at odds with each other and they were presented as two totally irreconcilable and adverse paths ...
Mohammad Fanaaii Eshkevari
doaj  

Philosophy of Intellect and Vision in the De anima and De intellectu of Alexander of Aphrodisias [PDF]

open access: yes, 2010
Alexander of Aphrodisias (fl. c. 198–209) was born somewhere around 150, in Aphrodisia on the Aegean Sea. He began his career in Alexandria during the reign of Septimius Severus, was appointed to the peripatetic chair at the Lyceum in Athens in 198, a ...
Hendrix, John S
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

INTELLECT VITAMINS

open access: yesПедиатрическая фармакология, 2007
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E.V. Shikh
doaj   +2 more sources

Plotinus: The First Philosopher of the Unconscious [PDF]

open access: yes, 2014
Plotinus is sometimes referred to as “the first philosopher of the unconscious.” In his 1960 essay “Consciousness and Unconsciousness in Plotinus,” Hans Rudolph Schwyzer called Plotinus “the discoverer of the unconscious.” What exactly was Plotinus ...
Hendrix, John S
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

An Interview with Masoud Yazdani, editor of London-based Intellect Books

open access: yesNANO, 2014
Sean Scanlan conducted an email interview with Masoud Yazdani, the editor of Intellect Books, an independent academic publisher in the fields of creative practice and popular culture, whose aim is to publish scholarly books and journals that provide a ...
Sean Scanlan, Masoud Yazdani
doaj  

An Income to the Philosophical School of Master Javadi Amoli [PDF]

open access: yesحکمت اسرا, 2018
The philosophical school of Professor Javadi Amoli follows Qom's sect and this sect define under Sadrai wisdom system. The present study try to present a phenomenological description of Ayatollah Javadi Amoli philosophical school.
میثم واثقی
doaj  

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