Results 91 to 100 of about 540,064 (342)

Evaluating the use of the Child and Adolescent Intellectual Disability Screening Questionnaire (CAIDS-Q) to estimate IQ in children with low intellectual ability [PDF]

, 2014
In situations where completing a full intellectual assessment is not possible or desirable the clinician or researcher may require an alternative means of accurately estimating intellectual functioning. There has been limited research in the use of proxy
A Auerbach, A Lüscher, A Paramekanti, AV Syromyatnikov, AW Sandvik, B Dalla Piazza, B. Dalla Piazza, C Gros, C Gros, C Kim, C Nayak, C-M Ho, C-Y Hou, CJ Hamer, CM Canali, D. A. Ivanov, D. F. McMorrow, DA Ivanov, DA Tennant, DP Kozlenko, DV Dmitriev, E Manousakis, F Franjic, G Baskaran, G Müller, G. J. Nilsen, H Bethe, H. M. Rønnow, HM Rønnow, J Simon, JD Reger, K Ishii, KW Plumb, L Balents, L Balents, L Braicovich, L Faddeev, M Calandra Buonaura, M Enderle, M Greven, M Guarise, M Jeong, M Kohno, M Mourigal, M. Enderle, M. Mourigal, ME Zhitomirsky, N Trivedi, N Tsyrulin, N Tsyrulin, N. B. Christensen, NB Christensen, NS Headings, OF Syljuåsen, P Ghaemi, P. Tregenna-Piggott, PW Anderson, R Coldea, R Coldea, RB Laughlin, RRP Singh, T Li, T-H Han, T. G. Perring, TC Hsu, TK Lee, W Zheng, WP Su, X-G Wen, Y Tang, YJ Kim, Z Liu   +71 more
core   +5 more sources

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source

TronicBoards: An Accessible Electronics Toolkit for People with Intellectual Disabilities [PDF]

, 2022
Hashini Senaratne, Swamy Ananthanarayan, Kirsten Ellis   +2 more
openalex   +1 more source

Arson treatment programmes for offenders with disability : a systematic review of the literature

, 2012
Purpose – The purpose of this paper is to identify and evaluate treatment for adult fire setters with an intellectual disability, given the specific risks they present, the complexities of criminal proceedings associated with their behaviour, and ...
Curtis, Ashlee, Day, Andrew, McVilly, Keith   +2 more
core   +1 more source

Early mortality and primary causes of death in mothers of children with ID or ASD: a retrospective cohort study [PDF]

, 2014
INTRODUCTION: Mothers of children with intellectual disability or autism spectrum disorder (ASD) have poorer health than other mothers. Yet no research has explored whether this poorer health is reflected in mortality rates or whether certain causes of ...
A Corrice, A Kouvonen, A Richdale, B Baker, B Petterson, C Bigby, C Thiel, D Lawrence, D Lawrence, D Norlin, E Calle, E Sen, Geoff Hammond, H Bourke-Taylor, H Eoh, H Leonard, H Leonard, Helen Leonard, J Caldwell, J Daniels, J Daniels, J Dumas, J Finsterer, J Sanders, J Smith, Jenny Bourke, Jenny Fairthorne, K Anderson, K Bjartveit, Katsuaki Suzuki, L Abbeduto, M Baker-Ericzén, M Olsson, M Polimeni, M Sawyer, M Watt, M Yeargin-Allsopp, P Black, Peter Jacoby, R Hagerman, R Hodapp, R Webster, S Rasmussen, S Rizk, Y Chida, Y Takahashi   +45 more
core   +3 more sources

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance

Advanced Science, EarlyView.
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar, Vishwa I. P. W. A. Kumara, Pradeepa C. G. Bandaranayake, Dong Yawen, Yang‐Yang Gao, Junfeng Liu, Ge‐Fei Hao, Xiu‐Fang Xin   +7 more
wiley   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

RE: Impact on psychiatrists in intellectual disability of Court of Protection orders for section 49 (Mental Capacity Act) reports: online survey

BJPsych Bulletin, 2023
Niraj Singh, Asit Biswas
doaj   +1 more source

Stalking, harassment, gendered abuse, and violence towards politicians in the COVID-19 pandemic and recovery era

Frontiers in Psychiatry
BackgroundHigh levels of harassment and threats against parliamentarians are being reported internationally, especially in the social media space. This is occurring alongside changes in our social landscape, with increasing political polarisation and the
Susanna Every-Palmer, Susanna Every-Palmer, Oliver Hansby, Oliver Hansby, Justin Barry-Walsh   +4 more
doaj   +1 more source

The concept of sexual exploitation in legislation relating to persons with intellectual disability [PDF]

, 2006
The focus of this paper is on the use of the concept of sexual exploitation in legislation concerning sexual expression by persons with mental impairment, with particular emphasis on persons with intellectual disability.
Graydon, C.M., Hall, G., O'Brien-Malone, A   +2 more
core   +1 more source