Results 61 to 70 of about 508,553 (288)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

The Effect of Exercise on Anxiety of Adolescents with Intellectual Disability

Physical Treatments, 2015
Purpose: The present study aimed to investigate the effect of exercise on the anxiety of adolescents with intellectual disability. Methods: Study method was quasi-experimental with pretest-posttest design and a control group.
Masoomeh Salehpoor, Mohsen Salesi, Ghorban Hemati Alamdarloo   +2 more
doaj  

Life expectancy of people with intellectual disability: a retrospective cohort study from New South Wales, Australia

BMJ Open
Objectives To comprehensively analyse the life expectancy at birth of people with intellectual disability, including people with Down syndrome, to inform health equity and service planning.Design Retrospective cohort study.Setting Residents of New South ...
Preeyaporn Srasuebkul, Julian Trollor, Julian Trofimovs   +2 more
doaj   +1 more source

Incidence and prevalence of falls in adults living with an intellectual disability living in the community: A systematic review [PDF]

, 2017
Review question/objective: The objective of this review is to synthesize the best available evidence to determine the incidence and prevalence of falls in adults with intellectual disability living in the ...
Bulsara, Caroline, Bulsara, Max, Downs, Jenny, Hill, Anne-Marie, Ho, Portia, Patman, Shane   +5 more
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Association of Borderline Intellectual Functioning and Adverse Childhood Experience with adult psychiatric morbidity. Findings from a British birth cohort

BMC Psychiatry, 2019
Background To examine whether Borderline Intellectual Functioning (BIF) and Adverse Childhood Experiences independently predict adult psychiatric morbidity.
Angela Hassiotis, Emma Brown, James Harris, David Helm, Kerim Munir, Luis Salvador-Carulla, Marco Bertelli, Amaria Baghdadli, Jannelien Wieland, Ramon Novell-Alsina, Jordi Cid, Laura Vergés, Rafael Martínez-Leal, Tuba Mutluer, Fuad Ismayilov, Eric Emerson   +15 more
doaj   +1 more source

Diagnosis by behavioral observationHome-Videosomnography – A Rigorous Ethnographic Approach to Sleep of Children with Neurodevelopmental Conditions

Frontiers in Psychiatry, 2015
Introduction Advanced video technology is available for sleep-laboratories. However, low-cost equipment for screening in the home setting has not been identified and tested, nor has a methodology for analysis of video recordings been suggested.MethodsWe ...
Osman Sevket Ipsiroglu, Osman Sevket Ipsiroglu, Osman Sevket Ipsiroglu, Yi-Hsuan Amy Hung, Forson eChan, Michelle eRoss, Dorothee eVeer, Sonja eSoo, Gloria eHo, Mai eBerger, Graham eMcAllister, Heinrich eGarn, Heinrich eGarn, Gerhard eKloesch, Adriano Vilela Barbosa, Sylvia eStockler, Sylvia eStockler, William eMcKellin, William eMcKellin, Eric eVatikiotis-Bateson   +19 more
doaj   +1 more source

Examination of parental and special education teachers' attitudes towards sports activities of students with intellectual disability [PDF]

, 2018
The purpose of this study was to examine the attitudes of parents of students with intellectual disability and special education teachers working in special education schools to the sports activities of students with intellectual disability (ID).The ...
Aslan, Şehmus
core   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

To the point - diabetes information for people with intellectual disability and their carers [PDF]

, 2004
Objective: To describe the perceptions and experiences of living with diabetes as told by people with intellectual disability and their carers and support staff. Design: Qualitative semi-structured interview study.
Boyle, Frances, Lennox, Nicholas, McPhee, Judith Helen, Rey-Conde, Therese Frances   +3 more
core