Results 91 to 100 of about 1,551,617 (305)

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz   +8 more
wiley   +1 more source

História da historiografia e temporalidades: notas sobre tradição e inovação na história intelectual

open access: yesAlmanack
Resumo Este ensaio tece alguns breves comentários a partir da leitura do texto Tradiciones electivas. Cambio, continuidad y ruptura en historia intelectual, de Javier Fernández Sebastián, procurando refletir sobre a questão da temporalidade na história ...
Fernando Nicolazzi
doaj   +1 more source

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht   +53 more
wiley   +1 more source

Minimally Clinically Important Difference of the Clinical Assessment Scale in Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The Clinical Assessment Scale in Autoimmune Encephalitis (CASE) tracks disease severity in autoimmune encephalitis (AE), but no threshold for significant change exists. We aimed to determine the minimally clinically important difference (MCID) for CASE.
Yihui Goh   +8 more
wiley   +1 more source

ON STUDYING SOME PROBLEMS OF INTELLECTUAL HISTORY OF THE SOVIET SOCIETY IN THE 1940s - 1990s

open access: yesГуманитарные и юридические исследования, 2021
The study reveals some controversial aspects of the Soviet social science and its study in Soviet historiography in the postwar period. The article presents the author's view about the nature of social Sciences and on their functioning in the Soviet ...
T. A. Bulygina
doaj  

Intellectual history [PDF]

open access: yes, 2018
Kaum einer der ins Deutsche eingewanderten Termini ist von so vielen Nachbarn umgeben wie 'intellectual history': Ideengeschichte, 'history of ideas', intellektuelle Geschichte, Intellektuellengeschichte, Intellektualgeschichte, Geistesgeschichte, Philosophiegeschichte, Wissensgeschichte, Wissenschaftsgeschichte, Begriffsgeschichte, Diskursgeschichte ...
openaire  

The Generation of Memory: Reflections on the “Memory Boom” in Contemporary Historical Studies [PDF]

open access: yes, 2012
Jay Winter delivered the following in the form of a lecture at the Canadian War Museum on 31 October 2000. A distinguished academic, Winter has been writing about the cultural history of the First World War for nearly three decades.
Winter, Jay
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich   +19 more
wiley   +1 more source

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