Results 211 to 220 of about 1,551,617 (305)

Clinical Characteristics of Arginase 1 Deficiency: Natural History Insights From International Clinical Trials. [PDF]

J Inherit Metab Dis
Rudebeck M, Braverman N, Chang R, Enns GM, Ghosh A, Gorce M, Karall D, Sharma R, Shelkowitz E, Zori R, McNutt M.   +10 more
europepmc   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Types and Diagnosis of Childhood Intellectual Disabilities: Advancing Accuracy for Better Outcomes. [PDF]

Children (Basel)
Babiker R, Sami MM, Ahmed HK, Salama RA.
europepmc   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Antipsychotic Use Among Intellectually Disabled Individuals With Rare Genetic Variants That Confer Risk for Schizophrenia. [PDF]

J Intellect Disabil Res
Colijn MA.
europepmc   +1 more source

A Physiological Microfluidic Blood–Brain‐Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation

Advanced Healthcare Materials, EarlyView.
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen, Neona M. Lowe, Sophia Kellogg, Kuan‐Wei Huang, Hannah O'Toole, Elizabeth J. Hale, Venktesh S. Shirure, Bhupinder S. Shergill, Steven C. George, Randy P. Carney   +9 more
wiley   +1 more source

Exploring the Relationship Between Diaphragmatic Ultrasound Parameters and Lipid Mediators in Chronic Obstructive Pulmonary Disease: A Case Control Study. [PDF]

Am J Mens Health
Jelassi W, Hedhli A, Hajtaeib S, Euchi K, Ben Fraj MK, Cheikhrouhou S, Ouahchi Y, Mjid M, Toujani S, Feki M, Dhahri B.   +10 more
europepmc   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Clean New World : Toward an Intellectual History of American Environmental Law, 1961-1990 [PDF]

, 2011
Blomquist, Robert F.
core   +2 more sources

The Perils of Autobiography: Evidence, Meaning, Reliability, and Context in the Historiographical Canon on Carl Ransom Rogers, 1950s-2020s. [PDF]

Integr Psychol Behav Sci
Fierro C.
europepmc   +1 more source