Results 231 to 240 of about 18,205 (310)

Open Science, Health Data and Epistemic Harms: A Multidisciplinary Reflection. [PDF]

Data Sci J
Chatikobo T, Griffiths F, Hayden N, Leeming G, Mishra A, Morris E, Schirru L, Sheehan N, Williams A, Sekalala S.   +9 more
europepmc   +1 more source

INTELLECTUAL PROPERTY (IP) COMMERCIALIZATION IN KENYA:

The journal of law, the Postgraduate Course of Kansai University
openaire   +1 more source

CaMKIIβ insufficiency disrupts cortical networks, producing aberrant low‐gamma oscillations and seizure susceptibility

Epilepsia, EarlyView.
Abstract Objective Pathogenic variants in the calcium/calmodulin‐dependent protein kinase II B gene (CAMK2B) have been associated with neurodevelopmental disorders, including epilepsy, yet the mechanisms underlying cortical dysfunction remain largely unclear.
Hiroki Mutoh, Kazushi Aoto, Atsuo Fukuda, Hirotomo Saitsu   +3 more
wiley   +1 more source

A translational multimodal machine‐learning prototype predicting valproate response in epilepsy treatment

Epilepsia, EarlyView.
Abstract Objective Epilepsy affects ~1% of the global population and often requires lifelong antiseizure medication (ASM) therapy. Valproic acid (VPA) is a commonly prescribed first‐line ASM, yet only approximately half of patients achieve sustained seizure freedom. Treatment selection remains largely empirical.
Simeon Platte, Afsheen Kumar, Giorgia Guerini, Massimo Pandolfo, Denise Haslinger, Colin B. Josephson, Guillermo Delgado‐García, Navprabhjot Kaur, Michaela‐Pauline Lux, Heiko Stempfle, Chantal Depondt, Reetta Kälviäinen, Felix Rosenow, Sophie von Brauchitsch, Karl Martin Klein, Andreas G. Chiocchetti   +15 more
wiley   +1 more source

Strategic solidarity: solidarity and self-interest in Scandinavian contributions to global Covid-19 vaccine equity. [PDF]

Global Health
Storeng KT, de Bengy Puyvallée A, Sandvik Ling E, Moe Fejerskov A.   +3 more
europepmc   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Author or prompter? Scientific writing, identity, and the Theseus paradox. [PDF]

Philos Ethics Humanit Med
Akgün M.
europepmc   +1 more source

Cannabidiol reduces atypical absence seizures and epileptic spasms in a Gabrb3+/D120N mouse model of Lennox–Gastaut syndrome

Epilepsia Open, EarlyView.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a drug‐resistant developmental and epileptic encephalopathy (DEE). Preclinical drug development for LGS is constrained by a lack of syndrome‐relevant animal models. We aimed to evaluate a Gabrb3+/D120N knock‐in (KI) mouse model of LGS by quantifying atypical absence seizures and epileptic spasms and ...
Thomas Harman, Laura A. Sharman, Ka Lai Yip, Miguel Bedoya‐Pérez, Vaishali Janve, Jonathon C. Arnold   +5 more
wiley   +1 more source

Facilitators and Barriers to Implementing Research Integrity Code of Conduct and Open Science Initiatives: Perspectives of Research Regulators in Kenya, Malawi and Uganda

Barugahare J, Kumwenda T, Mfutso-Bengo J, Kamuyu R, Bukusi E, Sseryazi IS, Mutumba B, Opolot H, Zeegers M, Gopalakrishna G.   +9 more
europepmc   +1 more source

Development of Data Transfer Ethics Framework (daTEF): A participatory approach to delivering evidence-based guidelines for healthcare data transfer. [PDF]

PLoS One
Syangtan G, Manandhar S, Bhattarai M, Shah B, Singh M, Rayamajhee B, Adhikari A.   +6 more
europepmc   +1 more source